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Pulmonology Board Review > Mediastinal and Other Neoplasms > Flashcards

Mediastinal and Other Neoplasms Flashcards

1
Q

4 lab tests to order in indeterminate anterior mediastinal tumors

A
  1. Anti-acetylcholine receptor antibody (Thymoma and myesthenia)
  2. Alpha-fetoprotien (Non-seminoma germ cell tumor)
  3. Beta-HCG (Non-seminoma germ cell tumor)
  4. LDH (Germ cell and lymphomas
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2
Q

Most common mediastinal lesions regardless of compartment

A
  1. Thymoma (anterior)
  2. Neurogenic neoplasm (posterior)
  3. Lymphomas (anterior/middle)
  4. Metastases (anterior/middle)
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3
Q

4 T’s of anterior mediastinal tumors

A
  • Thymoma
  • “Terrible” tumors (lymphoma and metastasis)
  • Teratomas (or any germ cell tumor but 2/3 are teratoma)
  • Thyroid (intrathoracic thyroid specifically)
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4
Q

Disease associated with thymomas

A

Myesthenia Gravis

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5
Q

Most common lymphoma that is primary mediastinal

A

Nodular sclerosing hodgkins lymphoma

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6
Q

Preferred biopsy method for thymoma

A

Surgical resection

Theoretical chance of seeding with core needle biopsy

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7
Q

most aggressive type of germ cell tumor in mediastinum

A

Non seminomatous

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8
Q

AFP and beta-HCG elevated in which germ cell tumor of mediastinum

A

Non-seminomatous

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9
Q

Treatment for seminomatous germ cell tumors

A

Radiation and/or chemo

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10
Q

Treatment for non-seminomatous germ cell tumors of mediastinum

A

cisplatin based combination chemotherapy

resection of residual tumor

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11
Q
A

Bronchogenic cyst in middle mediastinum

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12
Q
A

Pericardial cyst middle mediastinum

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13
Q
A

mediastinal lymphangioma

Benign but can infiltrate

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14
Q
A

Mediastinal lipomatosis

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15
Q

3 posterior mediastinum tumors

A
  1. Neurogenic neoplasms
  2. Esophageal lesions
  3. Miscellaneous
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16
Q

3 key features of neurogenic tumors in posterior mediastinum

A
  1. Mostly benign (70-80%)
  2. Acounts for 3/4 of primary posterior mediastinal tumors
  3. Asymptomatic in half the cases

Pulmonology Board Review (32 decks)

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