Lecture 18 Paediatric Endocrinology

Question 1

When investigating development FBC and ferritin test are looking for

Answer 1

General health
Coeliac
Crohn’s
JCA

Question 2

When investigating development U&Es, LFT, Ca and CRP tests are looking for

Answer 2

General health
Renal and Liver disease
Disorders of Ca metabolism

Question 3

When investigating development Coeliac serology and IgA tests are looking for

Answer 3

Coeliac disease

Question 4

When investigating development IGF-1, TFT, Prolactin, Cortisol tests are looking for

Answer 4

Hormonal disorders

Question 5

When investigating development Karyotype/Microarray tests are looking for

Answer 5

Turner’s syndrome

Chromosomal abnormalities

Question 6

What is the pubertal staging in girls

Answer 6

Breast budding

Tanner stage B2

Question 7

What is the pubertal staging in boys

Answer 7

Testicular enlargement
Tanner stage G2
T 4ml

Question 8

Name pathological causes of short stature

Answer 8

Undernutrition
Chronic illness (JCA, IBD, Coeliac)
Steroids
Hormonal
Syndromes (Turner, PW, Noonan)
Skeletal dysplasia

Question 9

What chromosomal mutation is associated with Prader-Willi syndrome

Answer 9

15q11-q13

Question 10

What is true pubertal development for boys and girls

Answer 10

Breast development in girls

Testicular enlargement in boys