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Pharmacology > B-Blockers > Flashcards

B-Blockers Flashcards

1
Q

Examples

A
  • Cardioselective (b1) - Bisoprolol, atenolol
  • Non-cardioselective (b1/2) - propanalol
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2
Q

Mechanism

A
  • Competitive inhibitor of b1 adrenoreceptors Inhibit activation of GPCR -> Reduced CAMP Less intracellular calcium -> Decreased ionotropy
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3
Q

Indications

A
  • Angina, MI, Hyperthyroidism, CHF
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4
Q

SE

A

Common: Dizziness/hypotension

Important: bronchoconstriction, bradycardia, hypoglycaemia, reynaud’s

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5
Q

CI

A
  • HF, PVD, Poorly controlled DM (can mask effects of hypoglycaemia)
  • Avoid in asthma, heart block, hypotension
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6
Q

Interaction

A
  • Alcohol (hypotensive effect)
  • Antiarrhythmics (bradycardia)
  • Anti-hypertensives
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Pharmacology (44 decks)

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