Digoxin Flashcards
1
Q
Class
A
Cardiac glycosides
2
Q
Mechanism
A
- Inhibits sodium potassium ATPase
- Prolongs phase 4 of cardiac AP
- Increase preload -> + Inotropic, - chronotropic
3
Q
Indications
A
- Rate control
- Heart failure
4
Q
A
5
Q
SE
A
Digoxin toxicity; narrow therapeutic window
Confusion
GI upset
Evidence of cardiotoxicity – palpitations, arrhythmias, conduction disturbances
Blurred or yellow vision
6
Q
CI
A
- Sick sinus syndrome
- Bradycardia (Heart block)
- WPW, Vtach, Vfib
- Hypokalaemia, hypercalcaemia
- Previous MI
