Syndrome of Inappropriate Secretion of ADH Flashcards
1
Q
What can cause SIADH?
A
Brain injury, infection, hypothyroidism, cancers, lung disease
2
Q
What happens in SIADH?
A
ADH is inappropriately released causing water to be reabsorbed in the collecting duct
3
Q
What are symptoms of SIADH?
A
Nausea and vomiting, headache, lethargy, cramps, weakness, confusion
4
Q
What are signs of SIADH?
A
Raised JVP, oedema, ascites
5
Q
What investigations would you do?
A
ADH levels, U&E, fluid status
6
Q
What are sodium and potassium levels?
A
Low sodium, normal potassium
7
Q
How do you manage SIADH?
A
Fluid restriction to increase osmolarity, treat underlying cause
8
Q
What are potential complications?
A
Cerebral oedema, seizure, coma
9
Q
What are plasma and urine osmolalities?
A
Plasma decreased, urine increased
