A:2. clinical use and Side effects of drug Flashcards Preview

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Flashcards in A:2. clinical use and Side effects of drug Deck (27)
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1

Famotidine

Cl: GERD, peptic, gastric ulcer
SE: Nausea, headache, skin rash, diarrea

2

Pantoprazol

Cl: GERD, Zolinger, Ulcer
SE:
- osteoporosis,
- hypergastrinemia
- bacterial overgrowth
- Leukopenia
- skin rash

3

Contraindication of antiacids

weak base ( increases the absorption)
weak acid ( warf, doxycycline) decrease absorprion

4

SE of lopramide, diphenoxylate

- RR decreased
- HR, Temp increase
- Dry mucous + skin

5

SE of palonosetron, ondansetron

- Increased QT time
- constipation
- dizziness

6

SE metoclopramide

- EPS
- Hyperprolactinemia

7

SE of ergotamin

- Increased BP
- GI ischemia
- central + peripheral vasospasm

8

SE Levodopa

- Hypotension, arrythima, nausea, Anorexia
- Hallucination, depression, dyskineasis

9

SE pramipexol, ropinirole

- Nausea, vomit, arrythima, Hypotension

10

SE ethusoximide

- Fatigue
- dizziness
- Gi distress
- SJS
- Headache

11

SE valproic acid

- Hepatotoxic
- Pancreatitis
- Alopecia
- Weight gain
- Teratogenic

12

SE lamatrogine

- SJS
- Hematologic disease

13

SE and Pk of Phenytoin

Pk: zero order kinetic of elimination, CYP450 +
SE: CNS depression, gingival hyperplasia, hirtuism, teratogenic.

14

Ix and SE of carbmazepine

Ix: Trigeminal neuralgia, central diabetes insipidus
SE: Teratogenic, SJS, increased ADH

15

SE of vigabatrin

- Visual loss
- psycosis
- sedation

16

SE phonobarbital

Sedation
resp depressin
hypotension
SJS

17

SE of Lithium

- Hypothyroidism
- Nephrogenic diabetes insipidus
- Decreased cardiac function
- Edema
- Teratogenic

18

SE SSRI

- Central: Psycosis, insomina, tremor, anxiety
- GI: Weightloss, diarreha nausea

19

SE reboxetine

Cardiotoxic

20

SE bupropion

- dry mouth, sweat, seizure, tremor

21

SE maoi

- Orthostatic hypotension
- Cheese effect
- Insomina
- Irritability
- Sexual disturbance

22

SE clozapine

Agranulocytosis
orthostatic hypotension
weight gain
sedation

23

Se 2nd gen antipsycotic

- Not as high EPs rest is: ort hypotension, sedation, weight gain

24

SE 1st gen antipsycotic

- EPS ( Dyskineasis)
- Dysphoria
- Endocrine dysfunction ( increased temp, weight)
- Muscarinic and alpha effect

25

Se: Benzodiazepine

- Sedation
- Tolerance
- Anterograde amnesia
- Resp depression (if underlying disease)

26

SE ketamine

Increased BP, ICP, Hallucination, no m. relax

27

SE Thiopental

decreased: BP, Resp, ICP,
INcreased: HR