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Flashcards in A workshop Deck (6)
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1

Flow chart of increase in SBP & DBP (starting from kidneys)

  • Kidneys → GFR → Na/H2O balance → ECF vol → Plasma vol → blood vol → venous pressure/vol → ↑VR → ↑ventricular filing (EDV) → ↑SV → ↑CO → ↑MAP → ↑SBP/DBP

2

Determinant of pulse pressure

  • SV
  • Arteriole compliance (also affects velocity of blood)
  • Reflected wave

3

What is the ejection fraction normally?

  • Only ~1/2 of EDV ejected per heart beat

4

Features of a reflected wave

  • Degree of reflection depends on TPR (↑TPR → ↑reflected wave)
  • Meets primary wave during diastole
  • BF in coronary A is during diastole as well

5

What occurs to the reflected waves as a result of age

  • ↑age → ↑stiffness of vessls → ↑velocity → reflected wave & primary wave meet during systole

6

Consequence of age on reflected waves

  • Results in ↑SBP & ↓DBP → ↑work of heart (needs to pump against higher pressure) → ↑need of O2 supply → Need to ↑blood in coronary A BUT DBP is low (& BF in coronary A is during diastole)