Abx Info Flashcards

1
Q

E. coli Abx

A
all BUT: 
penicillin 
diclox
vanc
clinda
metro
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2
Q

E. coli TEM-1 Abx

A

same as E. coli, EXCEPT ALSO NO amox/amp

all BUT: penicillin, diclox, vanc, clinda, metro, amox/amp

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3
Q

E. coli ESBL Abx

A

same as E. coli TEM-1, but ALSO NO cephalosporins and all others are +/- (all BUT: penicillin, diclox, vanc, clinda, metro, amox/amp, cephalos)

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4
Q

Klebsiella SHV-1 Abx

A

same as E-coli TEM-1 (all BUT: penicillin, diclox, vanc, clinda, metro, amox/amp)

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5
Q

Klebsiella KPC Abx

A
ONLY: 
chloramph
amino
cipro
levo
moxi
nitro
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6
Q

Bacteriodes fragilis Abx

A
ONLY: 
amox/clav
pip/tazo
carbapenems
clinda +/-
chloramph
metro
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7
Q

Name the gram (-) rods.

A
  1. Bacteriodes fragilis (sorta)
  2. E. coli (and E. coli TEM-1 and ESBL)
  3. Klebisiella (SHV-1 and KPC)
  4. Pseudomonas aeruginosa
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8
Q

Name the gram (+) cocci.

A

Staphs (MSSA and MRSA)
Streps (pyogenes, pneumoniae, viridans)
Enterobacter
VRE

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9
Q

Name the gram (+) rods.

A

C. diff, Clostriduim

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10
Q

Name the anaerobes.

A

C. diff, Clostridium

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11
Q

Name the weird ones (no cell wall, intracellular).

A

Chlamydia, Mycoplasma

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12
Q

Name the gram (-) cocci.

A

N. gonorrhoeae

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13
Q

N. gonorrhoeae Abx

A

ONLY:
3rd gen cephalosporin (ceftriaxone)
+/- macro
+/- tetracycline

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14
Q

Chlamydia Abx

A
(same as Mycoplasma)
ONLY:
macro
tetra
chloramph
cipro/levo/moxi
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15
Q

Mycoplasma Abx

A
(same as Chlamydia)
ONLY:
macro
tetra
chloramph
cipro/levo/moxi
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16
Q

MRSA Abx

A

ONLY:
vanc
nitro

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17
Q

C. diff Abx

A

ONLY:
vanc
metro

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18
Q

MSSA Abx

A
all BUT:
penicillin
amox/amp
chloramph
amino
metro
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19
Q

VRE Abx

A

ONLY:
chloramph +/-
nitro +/-

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20
Q

Entero Abx

A
ONLY: 
penicillin 
amox/amp
amox/clav
pip/tazo
vanc
nitro
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21
Q

Viridans strep Abx

A

all BUT:
amino
metro
cipro

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22
Q

S. pyogenes Abx

A

all BUT:

metro

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23
Q

S. pneumonia Abx

A

all BUT:
amino
metro

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24
Q

Pseudomonas Abx

A
ONLY:
pip/tazo
3rd and 4th gen cephalo (Ceftazidimine and Cefepime)
imp/dori/mero
amino
cipro
levo
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25
Penicillin treats which bugs?
streps and entero (gram +)
26
Dicloxacillin treats which bugs?
streps and MSSA (gram +)
27
Amox/amp treats which bugs?
strep, entero, E. coli (gram + and -)
28
Amox/clav treats which bugs?
same as amox/amp WITH MSSA, Klebsiella, bacteriodes (strep, MSSA, entero, E. colis, Klebsiella SHV-1, bacteriodes) (gram +, -, and anaerobes)
29
Pip/tazo treats which bugs?
same as pip/tazo WITH pseud (strep, MSSA, entero, E. colis, Klebsiella SHV-1, bacteriodes, pseudomonas) (gram +, -, and anaerobes)
30
1st gen Cephalosporins (cephalexin) treats which bugs?
normal gram + including MSSA, normal gram -
31
1st gen Cephalosporins (cephazolin) treats which bugs?
normal gram + including MSSA, normal gram -
32
2nd gen Cephalosporins (cefuroxime) treats which bugs?
normal gram + including MSSA, normal gram -, Clostridium perfringins
33
3rd gen Cephalosporins (Ceftriaxone) treats which bugs?
normal gram + including MSSA, normal gram -, Clostridium perfringins, AND N. gonorrhea
34
3rd gen Cephalosporins (Ceftazidime) treats which bugs?
normal gram + but not really MSSA, normal gram -, Clostridium perfringins AND pseudomonas
35
4th gen Cephalosporins (cefepime) treats which bugs?
normal gram + including MSSA, normal gram -, AND pseudomonas
36
Name the 2 carbapenems.
1. ertapenem | 2. imip/dori/mero-penem
37
Ertapenem treats which bugs?
normal gram + including MSSA, gram -, clostiridum perfringes, Bacteriodes (same as Imip/dori/mero-penem but NO pseudomonas)
38
Imip/dori/mero-penem treats which bugs?
same as Ertapenem but ADD pseudomonas (normal gram + including MSSA, gram -, clostiridum perfringes, Bacteriodes, pseudomonas)
39
Vanc treats which bugs?
all gram + INCLUDING MSSA and MRSA, Enterococcus; NO gram -; both Clostridiums (incl C. diff!)
40
Which drugs are the Beta-lactams?
penicillins, cephalosporins, and carbapenems
41
Which drugs are the cell wall synthesis inhibitors?
all the Beta-lactams (penicillins, cephalosporins, and carbapenems) AND vanc
42
Which drugs are the protein synthesis inhibitors?
``` macro tetracycline clinda chloramphenicol amino ```
43
What are the 3 fluoroquinolones?
1. cipro 2. levo 3. moxi
44
How are levo and moxi different?
levo treats pseudomonas
45
How is cipro different from levo?
cipro isn't as good at gram +
46
Which bugs will cipro treat?
sorta gram +, very gram -, pseudo, weird ones (chlamydia and mycoplasma)
47
Which bugs will levo treat?
gram +, very gram -, pseudo, clost, perfringens, weirdos
48
Which bugs will moxi treat?
gram +, very gram -, clost, perfringens, weirdos (same as levo but NO pseudomonas)
49
What bugs does nitrofuantoin treat?
very gram + including MSSA and MRSA with a little bit of VRE; very gram - (good at E. coli)
50
What bugs does metronidazole treat?
ONLY C. diff, C. perfringens, and Bacteriodes fragilis (the anaerobes)
51
Which drug only treats the anaerobes?
metro
52
Which drugs treat the weirdos (chlamydia and mycoplasma)?
macrolides, tetracycline, chloramphenicol, all fluoroquinolones (cipro, levo, moxi)
53
Vanc is N.O.T. trouble free.
nephrotoxicity, Ototoxicity, Thrombophlebitis
54
Protein synth. inhibitors: Buy AT 30, CCEL at 50.
AT = aminoglycosides (cidal); tetracycline (static) CCEL= Chloramphenicol, Clindamycin (static) Erythromycin (a macrolide- static) Linezolid (varies)
55
Which drugs should not be taken with milk, antacids, or iron?
tetra, fluoroquinolones
56
Which drugs are assoc. with superinfections?
C-FACT | Cephalosporins (2nd-3rd), Fluoroquinolones, Amox/amp, Clindamycin, Tetracycline
57
Which drug is mostly just used to treat bladder/UTIs?
nitro
58
Which drug can cause pseudomembranous colitis?
clinda
59
Which drug increases the Q-T interval?
fluoroquinolones
60
Which drugs are renally cleared?
FAT CCVP 1. fluoroquinolones 2. amino 3. tetra 4. carbapanems 5. cephalosporins 6. vanc 7. penicillin
61
Which drugs are hepatically excreted?
CRIMM 1. clinda 2. rifampin 3. isoniazid 4. metro 5. macro
62
Which drug induces P450?
rifampin
63
Which drug inhibits P450?
the macrolides
64
What does rifampin treat?
Tb
65
What does Isoniazid treat?
Tb