Flashcards in Acids Bases & Buffers Deck (11)
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1
What is the law of mass action?
A + B C + D
The rate (Vf) of the forward reaction is proportional to the product of [A] and [B]
Vf = Kf[A][B]
The rate (Vr) of the reverse eaction is proportional to the product of [C] and [D]
Vr = Kr[C][D]
2
Define pH
measure of acidity/ basicity
log[H+] + log[OH] = -14
pH + pOH = 14
solution is neutral if pH =pOH = 7
3
Deinfe pKa
log { ([H+][A-])/[HA] }
measure of the strength of an acid or base
lower pKa = stronger acid
higher pKa = stronger base
4
Whats is the Henderson-Hasselbalch equation for any given weak acid or base?
Ka = [H+][A-]/ [HA]
5
What is normal blood pH?
arterial: 7.34-7.44
venous: 7.28-7.42
6
What is normal blood pCO2?
40
7
How do weak acids and bases work to buffer pH?
By resisting change in pH
- max capacity at 1:1
- speed bump
8
What is the pH range of maximal buffering capacity?
[A-]/[HA] = 0.1-10
9
What is the H-H equation for the bicarbonate system?
pH = 6.1 + log[HCO3-]/0.3pCO2
10
What are the clinical presentations of a change in CO2 levels?
respiratory alkalosis (decrease in CO2)
respiratory acidosis (increase in CO2)
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