Acne Flashcards

1
Q

What is acne?

A

An inflammatory disease of the pilosebaceous follicle

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2
Q

How common is acne?

A

Over 80% of teenagers are affected by it.

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3
Q

What is the pathophysiology of acne?

A

Androgen conversion in puberty stimulates the sebaceous glands to produce sebum, which then blocks the glands.

There is inflammation and some secondary bacterial infection of the glands.

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4
Q

Does FHx have an impact on acne?

A

Yes - positive FHx increases risk of having it, and it being earlier in presentation and more severe.

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5
Q

Does acne affect girls and boys equally?

A

No, M>F.

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6
Q

When might a girl have a flare-up of acne?

A

When they are premenstrual.

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7
Q

With which gynaecological/endocrine condition is acne associated?

A

PCOS

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8
Q

How does acne present on the skin?

A

Greasy skin
Comedones
Papules
Pustules

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9
Q

When does acne present?

A

Usually at or just after start of puberty

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10
Q

Which areas of the body are affected by acne the most?

A

Face = 99% of cases

Back 60%
Chest 15%

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11
Q

What is severe acne with cysts called?

A

Nodulocystic acne

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12
Q

Which form of acne presents later in life?

A

Acne rosacea

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13
Q

A teenager presents to the GP quite distressed because of a recent onset of greasy skin with blackheads and pustules on the face and back.

Other than acne vulgaris, form a list of differentials.

A

Acne rosacea (middle/later life)

Folliculitis and boils

Milia (look similar to whiteheads)

Perioral dermatitis

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14
Q

Are any investigatons usually performed to investigate acne vulgaris?

A

No, not in a typical case.

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15
Q

What special circumstances might warrant further investigation into acne?

A

If there might be an underlying cause e.g. if an older pt develops acne they may have PCOS, virilising tumour etc.

If lesions look infected and treatment is needed.

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16
Q

When should a pt with acne vulgaris be referred to dermatology?

A

If the acne is severe and/or is having a large psychological impact

17
Q

What lifestyle advice can be given to pts with acne?

A

Keep face/back/chest clean.
Sunshine in moderation can help with acne in some people.
Avoid triggers if any have been noted e.g. some foods.

18
Q

How long do topical treatments for acne need to be used to produce effect?

A

6 weeks at least

19
Q

What topical therapies are available for mild acne vulgaris?

A
  • Benzoyl peroxide
  • Topical abx
  • Topical retinoids
20
Q

What do topical retinoids do for acne?

A

They break down comedones and have anti-inflammatory effect.

21
Q

When would oral therapies be used for acne?

A

In moderate to severe acne

22
Q

What oral therapies can be used to treat acne?

A
  • Oral abx
  • Oral anti-androgen for females
  • Oral retinoids
23
Q

What complications can occur secondary to acne?

A
  • Post-inflammatory hyperpigmentation
  • Scarring
  • Deformity
  • Psychological and social effects