Acute Gastroenteritis Flashcards

1
Q

What is gastroenteritis?

A

inflammation of the gastrointestinal tract that usually manifests with acute diarrhea, vomiting, and/or abdominal pain

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2
Q

What is infectious gastroenteritis?

A

gastroenteritis caused by pathogens moct commonly viruses but can also be causes bacteria, parasites and fungi

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3
Q

What is mild to moderate gastroenteritis?

A
  • Abdominal pain with normal abdominal examination
  • Mild diarrhea, nausea, and/or vomiting
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4
Q

What is severe gastroenteritis?

A

Gastrointestinal features
- Bloody stools
- Severe diarrhea, nausea, and/or vomiting
- Severe abdominal cramping and/or tenderness
Systemic features
- Fever (≥ 38.3°C) or sepsis
- Clinical signs of significant dehydration
- End-organ damage
- Duration > 1 week

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5
Q

Etiology?

A
  1. viral - most cases
  2. bacterial (20% of cases)
  3. parasites e.g. Giardia lamblia - should be considered in children with persistent diarrhea
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6
Q

Clinical features?

A
  1. nausea and vomiting
  2. fever
  3. abdominal pain
  4. diarrhea
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7
Q

What clinical features raise concern for severe illness?

A
  1. fever >40 degrees or tachypnea
  2. signs of poor peripheral perfusion
  3. bloody or bilious emesis
  4. petechiae
  5. altered mental status or excessive crying/fussiness
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8
Q

Important points in history?

A
  1. Diarrhoea - frequency of stools, number of days, blood or mucous in stools.
  2. Vomiting - frequency, blood, contents, associated with feeding
  3. Local reports of cholera outbreak or other contacts unwell
  4. Recent antibiotic or other drug treatment
  5. Attacks of crying with pallor in an infant - intussusception
  6. Feeding history
  7. Fever
  8. Local mankhwala (medicine)
  9. Urine Output
  10. Vaccination history (query Rotavirus)
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9
Q

Important points on examination?

A
  1. Assess for emergency signs ABCD
  2. Shock
    - cold hands, capillary refill >3 secs, fast, weak pulse
  3. Severe Malnutrition
    - visible severe wasting or oedema of both feet
  4. Assess Hydration
  5. Abdominal examination looking particularly for surgical problems
    e.g. distension, tenderness, guarding or a mass
  6. Is there any evidence of sepsis
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10
Q

Relevant investigations?

A
  1. Blood glucose
    - if low BCS, or lethargic
  2. Stool culture rarely indicated or available (but important if suspected cholera see below)
  3. Creatinine, urea and electrolytes/blood gases
    - if acidotic, poor urine output
  4. Blood culture
    - if high fever, long history, suspicion of Typhoid
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11
Q

Indications for admission?

A
  1. Gastroenteritis with severe dehydration
  2. Vomiting all oral fluids/ ORS or unable to receive oral fluids in A&E (i.e. lethargy)
  3. Social concerns
  4. Uncertainty about diagnosis
  5. Repeated presentation with no improvement in symptoms
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12
Q

Gastrointestinal causes of gastroenteritis?

A
  1. gastrointestinal causes of acute abdomen
    e.g. appendicitis, bowel obstruction
  2. inflammatory bowel disease
  3. congenital disorders with diarrhea
    e.g. Hirschprungs, intestinal malrotation with midgut volvulus, congenital diarrhea
  4. intussusception
  5. functional diarrhea
  6. antibiotic associated diarrhea
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13
Q

Extra-intestinal causes of gastroenteritis?

A
  1. pneumonia
  2. meningitis in children
  3. otitis media
  4. UTI in children and adolescents
  5. toxic shock syndrome
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14
Q

Treatment of gastroenteritis for all patients?

A
  1. Maintain adequate oral intake through breastfeeding or age-appropriate foods
  2. Zinc supplementation is recommended for patients with malnutrition or in low-income regions
  3. Educate patients and/or caregivers on preventing onward transmission of gastroenteritis
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15
Q

Treatment of mild to moderate gastroenteritis?

A
  1. Encourage fluid intake
  2. Give oral rehydration solution (ORS) if signs of moderate dehydration are present
  3. Advise caregivers to seek medical assistance if signs of significant dehydration develop
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16
Q

Treatment of severe gastroenteritis or children with admission criteria for dehydration?

A
  1. Admit to hospital and initiate contact precautions.
  2. Identify patients in shock and start IV fluid resuscitation.
  3. Initiate treatment of dehydration and electrolyte repletion with either IV fluids or ORS.
17
Q

Complications of gastroenteritis?

A
  1. dehydration
  2. malnutrition
  3. electrolyte imbalance
  4. reactive arthritis e.g. following infection from Salmonella, Shigella
  5. secondary lactase deficiency
    - may causes symptoms of lactose intolerance
18
Q

Prevention?

A
  1. food and water hygiene
  2. Educate patients and caregivers on preventing onward community transmission of infectious gastroenteritis
  3. Regular hand hygiene with soap and water including after changing diapers.
  4. Clean bathrooms, high-touch, and contaminated areas with bleach-based cleaners.