Acute Respiratory Distress Syndrome Flashcards Preview

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Flashcards in Acute Respiratory Distress Syndrome Deck (10)
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1

ARDS is respiratory failure a/w

- severe hypoxia
- low respiratory compliance

2

characteristic radiological changes

widespread pulmonary infiltrates

3

pulmonary artery occlusion pressure (PAOP)

low or normal

4

2 MCC of ARDS

1. sepsis
2. trauma

5

other causes of ARDS

- hemorrhage w/ hypotension
- transfusion
- obstetric emergencies
- cardiopulmonary bypass
- pancreatitis
- disseminated intravascular coagulation (DIC)
- fat embolus
- post cardiac arrest
- head injury
- aspiration
- smoke inhalation

6

onset of ARDS

rapid, usually < 24 hours of initial insult

7

clinical presentation of ARDS

- tachypnea
- dyspnea
- cyanosis

8

diagnosis of ARDS

- hypoxia
- low lung compliance
- widespread infiltrates on cxr
- known insult
normal left atrial pressure (indirect measurement by PAOP)
- PaO2/FiO2 27 kPa or 200 mmHg

9

ventilation for ARDS

- PEEP 5-18 cm H2O
- increase inspiratory times (increases intrinsic PEEP)
- small TV, < 7 ml/kg
- reduced FiO2, < 50% asap; acceptable hypoxemia (SaO2 > 88%)
- permissive hypercapnia
- +/- prone position

10

specific treatment for ARDS

- prostaglandin inhibitors
- anti-tumor necrosis factor Abs
- surfactant therapy
- oxypentifylline