ADD, Autism, Aspergers Flashcards

1
Q

Major feature of ADD

A

Paying too much attention to too many things (having little focus rather than too little attention)

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2
Q

Types of ADD

A
  • Attentional
  • Hyperactive/impulsive
  • Combined
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3
Q

Diagnostic criteria of ADD/ADHD

A
  1. Onset is NO later than 7 yo
  2. Symptoms present in 2 or more situations (school, home)
  3. Disturbance causes clinically significant distress or impairment in functioning
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4
Q

Diagnostic criteria of inattention/hyperactivity/impulsivity

A
  1. 6 or more symptoms
  2. Symptoms have been present for at least 6 months
  3. Symptoms are inappropriate for developmental level
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5
Q

Treatment of ADD

A
  • Behavioral psychotherapy with effective medication

- Stimulants (methylphenidate) 1st line: side effects MC anorexia w/wt loss, mood effects, tics

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6
Q

What is the 1st line pharm treatment of ADD? MC side effects?

A

Stimulants (meythlphenidate, dextroamphetamine)

  • Anorexia w/wt loss
  • Mood effects
  • Tics
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7
Q

Diet changes to treat ADD/ADHD

A

Ineffective

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8
Q

What is the origin of learning disorders?

A

Neurologic

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9
Q

What is the central clinical feature of a learning disorder?

A

Lack of normal developmental skill, either cognitive or linguistic

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10
Q

What does a learning disorder NOT include?

A

Learning problems caused primarily by:

  • Vision, hearing, motor impairments
  • Mental retardation
  • Emotional disturbance
  • Environmental, cultural, economic disadvantages
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11
Q

What is a reading learning disorder?

A

Dyslexia

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12
Q

What skills are impaired with reading learning disorder?

A

One or more impairments in the 3 skills necessary for reading:

  1. Word decoding
  2. Automaticity of letter and word recognition
  3. Understanding the meaning of words
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13
Q

What is the deficit of dyslexia?

A

Language processing - deficient decoding of phonemes (individual linguistic units, smallest detectable sound in a spoken word)

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14
Q

What are phonemes?

A
  • Smallest detectable sound in a spoken word

- Dyslexia is a deficient decoding of these

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15
Q

Define morpheme

A

Smallest meaningful speech sound

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16
Q

Define grapheme

A

Smallest unit in written language

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17
Q

What is the major phonetic processing consequence of dyslexia?

A

Cannot adequately pair the visually processed graphemes with their associated phonemes (reading problems)

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18
Q

Treatment of reading learning disorder

A
  • Referrals to special ed (SLP)
  • Treatment of comorbidities
  • Consider ophtho
  • Ocular training appears to be INEFFECTIVE
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19
Q

Ocular training for dyslexia?

A

Appears to be ineffective

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20
Q

Describe dysgraphia

A
  • Writing learning disorder

- Uncertain whether this exists as an isolated disorder (usually in combo with reading and other disorders)

21
Q

What does the process of writing connect?

A

Writing connects cognition, language, and motor skills

22
Q

Treatment of math learning disorder

A
  • Address specific subcomponent deficits
  • Exploit a child’s developmental strengths and subject area affinities
  • Bypass techniques (circumvent the deficient math task component)
  • Teach real life math
  • Improve curriculum in US
23
Q

Define autism generally

A

Persistent deficits in social communication and interaction across multiple contexts

24
Q

What is severity of autism based on?

A

Social communication impairments and restricted, repetitive patterns of behavior

25
How must symptoms present in autism to be diagnostic?
- Must be present in the early developmental period - BUT may not become fully manifest until social demands exceed limited capacities - OR may be masked by learned strategies in later life
26
What may explain some of the increased rates of PDD NOS?
- Screen time has increased - May reinforce repetitive behaviors in vulnerable children - Decreases amount of interpersonal interactions
27
What may explain hyperacoustic hearing in autistic patients?
Central auditory processing deficits that suggest distorted pathways between hearing and cortical processing
28
Diagnosis of PDD requires that features be present by when?
3 yo
29
Epidemiology of PDD
- Males 5:1 for PDD/autism - Males 10:1 for Aspergers - Increase in reported cases probably due to increased identification of cases
30
Clinical presentation of PDD
- Language development issues (especially receptive) - Poor social interaction - Sensory integration difficulties - Stereotypic behaviors
31
What does the AAP recommend for screening of PDD?
M-CHAT (Modified Checklist for Autism in Toddlers) | -Given at 18 and 24 months
32
What are critical items of the M-CHAT?
- Does your child imitate you? - Does your child respond to his/her name? - If you point at a toy, does your child look at it? - Does your child take interest in other children? - Does your child use index finger to point? - Does your child bring objects over to you?
33
What is Retts syndrome?
- X linked d/o in females (lethal in males) | - Leads to developmental reversals especially in expressive language, hand use, breath holding
34
What is Fragile X?
MC cause of inherited mental retardation - Flat feet, flexible joints, low muscle tone - Large body size, forehead, long face - Soft skin - Macroorchidism
35
What 2 disorders should be ruled out when evaluating for PDD?
Retts syndrome | Fragile X
36
Neuropsych testing for PDD
- Distinguish PDD NOS from a mood disorder | - Identify verbal and nonverbal learning disabilities
37
Treatment of PDD
- Antipsychotics | - Treatment of comorbidities (ADHD, OCD, etc.)
38
Pathophys of autism
Abnormalities of cellular configurations in several regions of the brain
39
Possible lab findings of autism
- High whole blood serotonin - Low serum biotinidase - High C-terminally directed beta-endorphin protein immunoreactivity - Oxidative stress - Hyperlacticacidemia - Mitochondrial disorders
40
MRI finding of autism
Enlargement of the total brain
41
Treatment goal of autism
EARLY identification - well meaning attempts not to "label" children can deprive them of specialized services
42
Pharm treatment of autism
No meds are efficacious for the core symptoms of autism
43
Antidepressants in treatment of autism?
Help with compulsions/repetitive behaviors
44
Features of Asperger syndrome
- Persistent impairment in social interactions - No significant aberrations or delays occur in language (UNLIKE AUTISM) - Limited capacity for spontaneous social interactions
45
Major difference between autism and Asperger's?
In Aspergers, there are no significant aberrations or delays in language
46
Life expectancy of Aspergers
Normal, except as impacted by comorbidities (especially depression)
47
Clinical presentation of Aspergers
- Peculiar and narrow interests - Sensitivity to sound, touch, pain, texture of foods - Synesthesia ("loud shirt") - Interprets language literally (sarcasm is difficult)
48
Treatment of Aspergers
- Adaptations to sensory abnormalities (sunglasses, earplugs) - Psychotherapy - Relaxation training - Encouragement of special skills - Meds are for comorbidities