Additonal 2019 Exam 3 questions Flashcards

1
Q
  1. Which has ADR of GI distress (constipation, abdominal pain, nausea, dyspepsia)
A

a. Colesevalam – (bile acid binding agent, not sure if this was the name used)

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2
Q
  1. Which of the following is a PCSK-9 inhibitor?
A

a. Evolocumab

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3
Q
  1. PCSK-9 normally
A

b. Promotes degradation of LDL receptors

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4
Q
  1. What is a negative effect of lipid parameter of bile acid binding agents
A

a. Increase TG

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5
Q
  1. ADR of STATIN
A

a. Myopathy

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6
Q
  1. Question over which can be used for similar results but with no cough as side effect?
A

a. -sartan

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7
Q
  1. IP3 activation results in what?
A

a. Ca release for SR

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8
Q
  1. Which binds factor Xa and prevents prothrombin converting to thrombin?
A

a. Apixaban

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9
Q
  1. Which can be used to increase salivary secretion in a patient?
A

a. Co-enzyme Q10

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10
Q
  1. Chamomile can be used to treat which radiation/chemo side effect?
A

a. Oral mucositis

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11
Q
  1. Which can be used to tx burning mouth?
A

a. Alpha-lipoic acid

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12
Q
  1. How to measure Argatroban?
A

a. aPTT

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13
Q
  1. Which is the shortest onset?
A

d. Cangrelor

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14
Q
  1. Which mediator binds to PAR-1?
A

a. Thrombin

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15
Q

x63. Which of the following does not have cGMP in mechanism?

A

a. Hydralazine

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16
Q
  1. Prostacyclin binds IP3, what is end result?
A

a. Stimulates AC, increase in cAMP

17
Q
  1. Which is the key mediator in fibronlysis?
A

a. Plasmin

18
Q
  1. What inhibits the final step in platelet aggregation?
A

a. Eptifibatide (or Abcixamab)

19
Q
  1. If cholesterol and TGs are absorbed from diet, which pathway is used?
A

a. Exogenous

20
Q
  1. Which is a direct thrombin inhibitor?
A

a. Argatroban (Dabigatran)