Adenoviridae

Question 1

What are the five recognized genera of Adenoviridae?

Answer 1

Mastadenovirus, Aviadenovirus, Atadenovirus, Siadenovirus, Ichtadenovirus

Question 2

What is the proposed sixth genus of Adenoviridae?

Answer 2

Testadenovirus

Question 3

Mastadenovirus primarily affects which species?

Answer 3

Mammals

Question 4

What unique proteins are found in Mastadenovirus?

Answer 4

Proteins V and IX

Question 5

What is the function of Protein V in Mastadenovirus?

Answer 5

Involved in viral DNA transport

Question 6

What is the function of Protein IX in Mastadenovirus?

Answer 6

Involved in transcription activation

Question 7

Aviadenovirus primarily infects which animals?

Answer 7

Birds

Question 8

Which unique structural protein is encoded by Atadenovirus?

Answer 8

p32K

Question 9

Atadenovirus lacks which immunomodulatory proteins found in Mastadenoviruses?

Answer 9

E3 region proteins

Question 10

Siadenovirus infects which groups of animals?

Answer 10

Birds, reptiles, and amphibians

Question 11

Ichtadenovirus primarily infects what kind of animals?

Answer 11

Fish

Question 12

Testadenovirus primarily infects what species?

Answer 12

Turtles

Question 13

What is the general structure of Adenoviridae virions?

Answer 13

Nonenveloped, hexagonal outline, icosahedral symmetry

Question 14

How many fibers project from each vertex of Mastadenovirus capsids?

Answer 14

One fiber

Question 15

How many fibers project from each vertex of Aviadenovirus capsids?

Answer 15

Two fibers

Question 16

What is the genome structure of Adenoviridae?

Answer 16

Linear double-stranded DNA (dsDNA)

Question 17

Where does adenovirus replication occur in the host cell?

Answer 17

Nucleus

Question 18

What is the main structural protein responsible for neutralization in Adenoviridae?

Answer 18

Hexon protein

Question 19

What plays a role in containing cell-binding ligands for attachment in Adenoviridae virions

Answer 19

Penton fibers

Question 20

How are Adenoviridae virions released from the host cell?

Answer 20

Cell lysis

Question 21

What feature distinguishes cells infected with Adenoviruses under a microscope?

Answer 21

Intranuclear inclusion bodies in procrystalline arrays

Question 22

What proteins induce cell-cycle progression and protect cell lysis during Adenoviridae replication?

Answer 22

E1A

Question 23

Which tumor suppressor gene is inactivated by E1A and E1B proteins?

Answer 23

p53

Question 24

What syndrome is caused by Canine adenovirus 1 (CAV-1)?

Answer 24

Infectious canine hepatitis

Question 25

What clinical sign can result from CAV-1 infection or vaccination?

Answer 25

Blue Eye (Corneal Edema)

Question 26

What diagnostic test detects viral genetic material of Adenoviridae?

Answer 26

Polymerase Chain Reaction (PCR)

Question 27

Which organ systems are primarily affected by Reptilian Adenoviruses?

Answer 27

Liver and gastrointestinal tract

Question 28

What disease is caused by Canine adenovirus 2 (CAV-2)?

Answer 28

Localized respiratory disease (potential cause of kennel cough)

Question 29

Between the two CAV-1 and CAV-2 who causes systemic diseases?

Answer 29

CAV-1

Question 30

Between the two CAV-1 and CAV-2 who causes localize diseases?

Answer 30

CAV-2

Question 31

Where is Equine Adenovirus 1 commonly isolated?

Answer 31

Upper respiratory secretions of foals and horses without disease

Question 32

Where is Equine Adenovirus 2 isolated?

Answer 32

Lymph nodes and feces of foals with respiratory disease and diarrhea

Question 33

What conditions are associated with Bovine Adenovirus infections?

Answer 33

Pneumonia, enteritis, conjunctivitis, keratoconjunctivitis, and weak calf syndrome

Question 34

What diseases are linked to Ovine Adenovirus infections?

Answer 34

Respiratory and enteric infections in lambs

Question 35

What diseases are caused by Porcine Adenovirus?

Answer 35

Respiratory, enteric infections, encephalitis (rarely severe)

Question 36

What virus causes Quail Bronchitis?

Answer 36

Fowl aviadenovirus A

Question 37

What virus causes Hydropericardium Syndrome (Angara Syndrome)?

Answer 37

Fowl aviadenovirus C

Question 38

What virus causes Egg Drop Syndrome?

Answer 38

Egg Drop Syndrome Virus

Question 39

What species are primarily affected by Egg Drop Syndrome Virus?

Answer 39

Laying hens

Question 40

What disease causes drop in egg production, soft-shelled or shell-less eggs, internal egg laying, decreased egg quality

Answer 40

Egg Drop Syndrome

Question 41

What treatment exists for Egg Drop Syndrome?

Answer 41

No treatment

Question 42

Canine Adenovirus 1 is under what genus?

Answer 42

Mastadenovirus

Question 43

Canine Adenovirus 2 is under what genus?

Answer 43

Mastadenovirus

Question 44

Equine Adenovirus 1 belongs to what genus?

Answer 44

Mastadenovirus

Question 45

Equine Adenovirus 2 belongs to what genus?

Answer 45

Mastadenovirus

Question 46

Murine Adenovirus 1 belongs to what genus?

Answer 46

Mastadenovirus

Question 47

Murine Adenovirus 2 belongs to what genus?

Answer 47

Mastadenovirus

Question 48

Bovine Adenovirus belongs to what genus?

Answer 48

Mastadenovirus

Question 49

Ovine Adenovirus belongs to what genus?

Answer 49

Mastadenovirus

Question 50

Porcine Adenovirus belongs to what genus?

Answer 50

Mastadenovirus

Question 51

Quail Bronchitis Virus belongs to what genus?

Answer 51

Aviadenovirus

Question 51

Hydropericardium Syndrome Virus belongs to what genus?

Answer 51

Aviadenovirus

Question 52

Egg Drop Syndrome Virus belongs to what genus?

Answer 52

Atadenovirus

Question 53

Odocoileus Adenovirus 1 belongs to what genus?

Answer 53

Atadenovirus

Question 53

Bovine Adenovirus D (types 4, 5, and 8) belongs to what genus?

Answer 53

Atadenovirus

Question 54

Hemorrhagic Enteritis Virus (HEV) belongs to what genus?

Answer 54

Siadenovirus

Question 55

Marble Spleen Disease Virus belongs to what genus?

Answer 55

Siadenovirus

Question 56

Avian Adenovirus Splenomegaly belongs to what genus?

Answer 56

Siadenovirus

Question 57

"Adeno" from Adenoviridae means?

Answer 57

Gland