Herpesvirales

Question 1

What are the three families of Herpesvirales?

Answer 1

Herpesviridae, Alloherpesviridae, Malacoherpesviridae

Question 2

Herpesviridae infects what types of animals?

Answer 2

Mammals, birds, and reptiles

Question 3

Alloherpesviridae infects what types of animals?

Answer 3

Fish and amphibians

Question 4

Malacoherpesviridae infects what types of animals?

Answer 4

Invertebrates, such as oysters and abalone

Question 5

The Herpesviridae family is divided into which subfamilies?

Answer 5

Alphaherpesvirinae, Betaherpesvirinae, Gammaherpesvirinae

Question 6

What is the primary latency site of Alphaherpesvirinae?

Answer 6

Sensory neurons

Question 7

What is the primary latency site of Betaherpesvirinae?

Answer 7

Monocytes, macrophages, and kidneys

Question 8

What is the primary latency site of Gammaherpesvirinae?

Answer 8

B and T lymphocytes

Question 9

What is the structure of Herpesvirales virions?

Answer 9

Large, enveloped with an icosahedral capsid

Question 10

What is the genome structure of Herpesvirales?

Answer 10

Linear double-stranded DNA (dsDNA)

Question 11

Where does Herpesvirales replication occur?

Answer 11

In the nucleus

Question 12

What are the intranuclear inclusion bodies associated with Herpesvirales?

Answer 12

Sites of viral replication and assembly

Question 13

What is the common transmission route for alphaherpesviruses?

Answer 13

Direct contact

Question 14

What family of Herpesvirales is associated with respiratory droplet transmission?

Answer 14

Herpesviridae

Question 15

Which family of Herpesvirales is primarily transmitted vertically?

Answer 15

Alloherpesviridae

Question 16

What characteristic feature defines Herpesvirales infections?

Answer 16

Latency and reactivation

Question 17

What triggers reactivation of latent Herpesvirales infections?

Answer 17

Stress, immunosuppression, or concurrent infections

Question 18

This subfamily of Herpesviridae has fast replication, causes acute lytic infection

Answer 18

Alphaherpesvirinae

Question 19

This subfamily of Herpesviridae has slow replication

Answer 19

Betaherpesvirinae

Question 20

These are Significant pathogens in aquaculture, causing mortality in juvenile oysters.

Answer 20

Malacoherpesviridae

Question 21

This is the hallmark feature of Herpesvirales

Answer 21

Latency

Question 22

What disease is caused by Gammaherpesvirinae in atypical hosts?

Answer 22

Malignant catarrhal fever

Question 23

What stage of replication involves viral DNA replication in Herpesvirales?

Answer 23

Early (β) gene expression

Question 24

What stage of replication involves the production of structural proteins in Herpesvirales?

Answer 24

Late (γ) gene expression

Question 25

During which stage of replication does immune evasion primarily occur in Herpesvirales?

Answer 25

Immediate Early (α) gene expression

Question 26

How are new Herpesvirales virions released from the host cell?

Answer 26

By budding from the nuclear membrane

Question 27

Herpesvirales acquire its envelope from the?

Answer 27

Host's Nuclear Membrane

Question 28

Bovine herpesvirus 1 causes what diseases?

Answer 28

1. Infectious Bovine Rhinotracheitis 2. Infectious Pustular Vulvovaginitis 3. Balanophosthitis

Question 29

Bovine herpesvirus 2 causes what disease?

Answer 29

1. Ulcerative mammillitis 2. Pseudo-lumpy skin diseases

Question 30

Suid Herpesvirus 1 causes what disease?

Answer 30

Pseudorabies/Aujeszky's Disease

Question 31

Equid Herpesvirus 1 causes what disease?

Answer 31

1. Equine Abortion 2. Equine Herpesvirus Myeloencephalopathy (EHM)

Question 32

Equid Herpesvirus 3 causes what disease?

Answer 32

Equine Coital Exanthema (ECE)

Question 33

Equid Herpesvirus 4 causes what disease?

Answer 33

Equine Rhinopneumonitis (ERP)

Question 34

Felid Herpesvirus 1 causes what disease?

Answer 34

Feline Viral Rhinotracheitis

Question 35

Gallid herpesvirus 1 causes what disease?

Answer 35

Infectious Laryngotracheitis (ILT)

Question 36

Gallid herpesvirus 2 causes what disease?

Answer 36

Marek’s Disease

Question 37

The herpesvirales virion is made up of?

Answer 37

Virion is made up of core, capsid, tegument