adernal Flashcards
1
Q
1. Typical sign of pheochromocytoma, except: Select one: a. constipation b. hypertension developed in paroxysm c. nausea, vomiting d. hyperhidrosis e. 24 hours urine VMA↑
A
a
2
Q
- True statements:
Select one or more:
a. glucocorticoids are synthesized in zona glomerulosa
b. mineralocorticoids are synthesized in zona fasciculata
c. mineralocorticoids are synthesized in zona glomerulosa
d. glucocorticoids are synthesized in zona fasciculata
A
c/d
3
Q
3. Conn-syndrome is not associated with: Select one: a. adenoma b. 21-hydroxylase deficiency c. 17α-hydroxylase deficiency d. hyperplasia e. 11ß-hydroxylase deficiency
A
b
4
Q
4. Which endocrine disease can cause hypotension? Select one or more: a. 21-hydroxylase deficiency b. Sheehan-syndrome c. hypothyroidism d. 11-β-hydroxylase deficienc
A
a/b/c
5
Q
5. True statements for pheochromocytoma: Select one or more: a. extramedullary in 10% b. malignant in 10% c. unilateral in 10% d. acquired in 10%
A
a/b
6
Q
6. Effects of glucocorticoids: Select one or more: a. stimulate bone resorption b. increase protein synthesis c. increase gluconeogenesis d. increase water and Na+-excretion
A
a/c
7
Q
7. Clinical signs of Cushing-syndrome: Select one or more: a. central obesity b. hypotension c. virilization d. psychological disorders
A
a/d
8
Q
8. Signs of Conn's syndrome: Select one or more: a. metabolic acidosis b. hypertonia c. hyperkalemia d. polyuria, polydipsia
A
b/d
9
Q
9. Clinical signs of pheochromocytoma: Select one or more: a. cold limbs b. sweating c. headache d. palpitation
A
a/b/c/d
10
Q
10. Effects of glucocorticoids, except: Select one: a. gluconeogenesis b. se glucose↑ c. collagen synthesis ↑ d. GFR↑ e. eosinopenia
A
c
11
Q
11. Which endocrine disease can cause hypotension? Select one or more: a. Sheehan-syndrome b. Addison-disease c. Waterhouse–Friderichsen-syndrome d. Cushing-syndrome
A
a/b/c
12
Q
12. Synthesized by the zona glomerulosa cells in the adrenal cortex: Select one: a. cortisol b. androgens c. 11-deoxycortizol d. dehydroepiandrosterone e. aldosterone
A
e
13
Q
- Characteristic findings in Cushing-syndrome:
Select one or more:
a. random secretion of ACTH
b. absence of normal diurnal rhythm
c. TSH-, GH-, LH-, FSH-secretion are increased
d. Hyperpigmentation
A
a/b
14
Q
14. The most common cause of chronic primary adrenocortical insufficiency: Select one: a. tumor metastasis b. hemorrhagic necrosis 73
c. tuberculosis
d. fungal infection
e. autoimmune
A
e
15
Q
- True statement for secondary mineralocorticoid-excess:
Select one:
a. all of them
b. se renin level is low
c. can occur in liver-cirrhosis
d. can be due to 11β-hydroxylase deficiency
e. can be due to SIADH
A
c
16
Q
16. Clinical signs of Cushing-syndrome, except: Select one: a. hirsutism b. dysmenorrhea c. osteoporosis d. depression e. Amenorrhea
A
b
17
Q
17. Clinical signs of Cushing-syndrome, except: Select one: a. depression b. livid striae c. amenorrhea d. virilization e. central obesity
A
d
18
Q
18. Cause of secondary mineralocorticoid excess with hypertension, except: Select one: a. accelerated hypertension b. Bartter-syndrome c. renovascular disease d. estrogen therapy e. reninoma
A
b
19
Q
- characteristic finding in ectopic ACTH-syndrome:
select one or more
a. Hyperkalemia
b. Hyperpigmentation
c. Usually the typical symptoms of Cushing syndrome are missing
d. Random secretion of ACTH
A
b/c/d
20
Q
20. synthesized by the zona fasciculate cells in the adrenal cortex: elect one a. Dehydroepiandrossterona b. Corticosterone c. Aldosterone d. Androgens e. Cortisol
A
e
21
Q
21. signs of acute Addisonian crisis, except: select one a. Fever b. Hypotension and shock c. Hypoglycemia d. Edema
A
d
22
Q
22. possible cause of Conn's syndrome, except: select one or more a. Adrenocortical hyperplasia b. 11-alpha-hydroxylase deficiency c. 21-alpha-hydroxylase deficiency d. Bartter syndrome
A
c/d
23
Q
23. which of the followings cannot cause secondary adrenocortical insufficiency? Select one or more a. Sheehan syndrome b. Glucocorticoid therapy c. Addison's disease d. Waterhouse-Friderchsen syndrome
A
c/d
24
Q
24. 17-ketosteroids in urine are the metabolite of: Select one: a. androgens b. estrogens c. mineralocorticoids d. none of them e. glucocorticoid
A
a
25
```
25. clinical signs of acute adrenocortical insufficiency, except:
select one
a. Dehydration
b. Hypoglycemia
c. Hypotension
d. Hypernatremia
e. Nausea
```
d
26
```
26. Signs of primary adrenocortical insufficiency:
Select one or more:
a. hypertension
b. GI disturbances
c. vitiligo
d. weakness, fatigue, losing weight
```
b/d
27
```
27. Which endocrine disease can cause hypertension?
Select one or more:
a. Cushing-syndrome
b. acromegaly
c. hyperprolactinemia
d. diabetes insipidus
```
a/b
28
```
28. Causes of secondary hyperaldosteronism:
Select one or more:
a. cardiac decompensation
b. liver cirrhosis
c. nephrotic syndrome
d. diuretic therapy
```
a/b
29
```
29. Typical signs of 11-b-hydroxylase deficiency:
Select one or more
a. Hypokalemia
b. Hypertonia
c. Hirsutism
d. Early adrenarche
```
a/b/c/d
30
```
30. Clinical signs of the secondary adrenocortical insufficiency, except;
select one
a. Anemia
b. Lymphocytosis
c. Dehydration
d. Eosinophilia
e. Low ACTH
```
c
31
```
31. Clinical signs of chronic adrenocortical insufficiency, except;
Select one
a. Hyperglycemia
b. Weight loss
c. Hyponatremia
76
Pathophysiology 1 MCQs - Team effort
d. Abdominal pain
e. orthostatic hypotension
```
a
32
```
32. hypertension can develop due to
select one or more
a. conn-syndrome
b. 11-b-hydroxylase deficiency
c. sheehan-syndrome
d. hyperthyroidism
```
a/b/d
33
```
33. Synthesized by the zona fasciculata cells in the adrenal cortex
select one
a. dehydroepiandrosterone
b. cortisol
c. androgens
d. corticosterone
e. aldosterone
```
b
34
```
34. Clinical signs of chronic primary adrenocortical insufficiency, except:
Select one:
a. GI disturbances
b. hyperpigmentation
c. muscle weakness
d. hypotension
e. hypernatremia
```
e
35
```
35. Possible causes of secondary hyperaldosteronism:
Select one or more:
a. Bartter-syndrome
b. cirrhosis
c. renovascular disease
d. estrogen therapy
```
a/b/c/d
36
```
36. Which of the test can be used to diagnose pheochromocytoma?
select one or more
a) Chromatogranin A
b) Se metanephrine, normetanephrine
c) Clonidine suppression test
d) 1311-MIBG scan
```
a/b/c/d
37
36. Hyperaldosteronism may develop due to
77
a) Tuberculosis
b) Cirrhosis
c) Bartter-syndrome
d) Estrogen therapy
b/c/d
38
```
37. Possible cause of Conn’s syndrome, except
select one
a) Bartter-syndrome
b) 21a-hydroxylase-deficiency
c) Adrenocortical hyperplasia
d) 17a-hydroxylase-deficiency
```
a/c
39
```
40. Synthesized by the zona reticularis cells in the adrenal cortex:
Select one:
a. cortisol
b. 11-deoxycortizol
c. corticosterone
d. dehydroepiandrosterone
e. aldosterone
```
d
40
41. Characteristic findings in ectopic ACTH-syndrome:
Select one or more:
a. hyperpigmentation
b. usually the typical symptoms of Cushing syndrome are missing
c. hyperkalemia
d. random secretion of ACTH
a/b/d
41
```
42. 17-OH-corticosteroids are the metabolite of:
Select one:
a. mineralocorticoids
b. none of them
c. androgens
d. Glucocorticoids
e. estrogens
```
d
42
43. True statements for pheochromocytoma:
Select one or more:
a. warm, red limbs
b. hypertension develops in paroxysm
c. weight gain
d. orthostatic hypotension can be observed between attacks
b/d
43
```
44. Possible causes of Conn's syndrome:
Select one or more:
a. 17α-hydroxylase-deficiency
b. adrenocortical hyperplasia
c. Bartter-syndrome
d. 21α-hydroxylase-deficiency
```
a/b
44
```
45. Signs of primary hyperaldosteronism:
Select one or more:
a. hypokalemia
b. edema
c. polyuria
d. acidosis
```
a/c
