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HISTOLOGÍA > Adipose Tissue > Flashcards

Adipose Tissue Flashcards

(66 cards)

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1
Q

Adipose tissue normally representa

A

15% to 20%

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2
Q

Celula estructural que forma al tejido adiposo

A

Adipocito

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3
Q

Acumula triglicéridos, fósfolipidos y colesterol principalmente en su citoplasma

A

Adipocito

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4
Q

En el estroma del tejido adiposo se encuentra

A

Tejido conjuntivo reticular y vasos capilares

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5
Q

Los adipocitos acumulan las grasas en su citoplasma en forma de

A

Gotas o inclusiones es decir no rodeadas por membrana celular

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6
Q

Los lípidos no se fijan adecuadamente y se disuelven en disolventes orgánicos utilizados para deshidratación como

A

Chileno y alcohol

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7
Q

Para fijar la estructura de los adipocitos se debe utilizar fijadores específicos como

A

Osmio o bien por congelación de tejido

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8
Q

La tincion para los lípidos para microscópia óptica requiere el uso de colorantes liposolubles como

A

Sudanes o el rojo O al aceite

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9
Q

Dos variedades de tejido adiposo

A

Tejido adiposo unilocular y multilocular

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10
Q

Constituido por adipocitos con una sola cavidad, los cuales pueden aparecer dispersos En cualquier parte del cuerpo que contenga TC reticular o laxo,

A

Tejido adiposo unilocular

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11
Q

El parenquima del tejido adiposo unilocular está formado por

A

TC laxo o reticular

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12
Q

El estroma del tejido adiposo unilocular está formado

A

TC reticular y abundantes capilares sanguíneos

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13
Q

Diámetro de los adipocitos maduros cuyo citoplasma esta ocupado por una gota de grasa

A

100 micrómetros

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14
Q

Forma del adipocitos uniloculares

A

Anillo de sello, un delgado anillo periférico a la gota de grasa y el nucleo se sitúa en la esquina del mismo

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15
Q

Rodean a cada adipocito formando una cesta a su alrededor

A

Fibras de reticulina

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16
Q

Puede observarse con claridad el aspecto de las gotas de grasa que aparecen homogéneas y oscuras debido a la presencia de

A

Osmio

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17
Q

El tejido adiposo unilocular se encuentra en

A

Masas discretas (cuerpos grasos) , gras subcutánea( hipodermis), tejido adiposo retroperitoneal y mesenterios

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18
Q

Esta variedad de tejido adiposo esta especializada en acumular grasa que actúa como sustancia de reserva de forma que en la fase de ingesta el exceso energético (glucosa y lípidos) que pasan por la sangre son acumulados en

A

Tejido adiposo unilocular

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19
Q

Forma de liberación de reservas lípidicas

A

Glicerol y ácidos grasos

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20
Q

Adipocito con forma poligonal y un tamaño de 50 micrómetros que se caracteriza por contener pequeñas gotas de grasa en su citoplasma y el núcleo ocupa una posición central

A

Tejido adiposo plurilocular

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21
Q

Citoplasma presenta aspecto espumoso con zonas acidofilas con acumulos de retículo liso y mitocondrias

A

Tejido adiposo plurilocular

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22
Q

Tejido adiposo unilocular está bajo control

A

Hormonal

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23
Q

Presente en periodos neonatal , con función termogenica, y muestran una localización restringida

A

Tejido adiposo Pardo o plurilocular

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24
Q

Recuerdan a las glándulas pluricelulares por la disposición en lóbulos y lobulillos y escasos espacios intercelulares

A

Tejido adiposo Pardo

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25
Se le denomina epitelioide
Tejido adiposo plurilocular
26
Especializados en la producción de calor a partir de la oxidación mitocondrial de los derivados de las grasas
Tejido adiposo Pardo
27
Desacoplamiento del proceso de la fosforilacion oxidativa en las mitocondrias y la energía se disipa en forma de calor protegiendo de la hipotermia regulando la temperatura corporal
Termo génesis
28
Caloric density of triglycerides
9.3 kcal/g
29
The most eficient nutrient storage
Triglycerides
30
Adipocytes respond to
Nervous and hormonal stimuli
31
The more common type
White adipose tissue
32
Diameter of cells of white adipose tissue
50 to 150 micrometers diameter
33
Unilocular adipocytes can generate benign tumors that are common called
Lipomas
34
Malignant adipose tumors
Liposarcomas
35
Fetal Lipomas of brown fat are sometimes called
Hibernomas
36
In white adipose cells the lipid droplet Cytoplasm interface is reinforced by intermediate filaments of
Vimentin
37
The color of white adipose tissue depends on
The diet, amount of carotenoids dissolved in lipids
38
Triglycerides stored by cells of white adipose tissue can be derived from dietary fats brought to adipocytes as circulating
Chylomicrons
39
Particles up to 1200 nm in diameter form in intestinal epithelial cells and transported in blood plasma and lymph
Chylomicrons
40
Consist of a central core of triglycerides and cholesterol esters, surrounded by apolipoproteins
Chylomicrons
41
In adipose tissue both Chylomicrons and VLDL are hydrolyzed at the luminal surfaces of blood capillaries by
Lipoproteins lipase
42
An enzyme synthesized by adipocyte and transferred to the capillary cell membrane
Protein lipase
43
Synthesis by adipocytes of fatty acids from glucose is accelerated by , which also stimulates the uptake of glucose into adipocytes and increases the synthesis of lipoprotein lipase
Insulin
44
Released by postganglionic sympathetic nerves in adipose tissue
Norepinephrine
45
Norepinephrine Released by postganglionic sympathetic nerves in adipose tissue activates
Hormone sensitive lipase
46
Breaks down triglycerides at the surface of the stored lipid droplets
Hormone sensitive lipase
47
The free fatty acids diffuse across the membranes of the adipocytes and the capillary endothelium and bind the carrier protein... In blood for transport throughout the body
Albumin
48
The more water soluble glycerol remains free and is Taken up by the
Liver
49
Inhibits the hormone sensitive lipase, reducing fatty acid realease and also stimulates enzymes for lipids synthesis.
Insulin
50
Promote triglycerides breakdown and release of fatty acids
Glucagon and growth hormone
51
Adipocytes are the Sole source of the 16kDa polypeptide hormone called
Leptin
52
Satiety factor , regulate the apetite under normal conditions and participates in regulating the formation of new adipose tissue
Leptin
53
Locations of adipose tissue that resist long period of starvation
Palms, soles and retro orbital
54
Most unilocular adipocytes lose nearly all their fat and become polyhedral or spindle-shaped with very small lipid droplets
Starvation
55
White adipose tissue begin to accumulate at the week
30 week of gestation
56
Adipocytes can differentiate from mesenchymal stem cells throughout life , adult-onset obesity Mainly involves increase size of existing adipocytes
Hypertrophic obesity
57
Involves increase in both adipocyte size and Numbers due to differentiation of more preadipocytes from mesenchymal stem cells
Hyperplastic obesity
58
Brown adipose tissue constituted
2 % to 5% of newborn body weight
59
Located Brown adipose tissue in
Back, neck, and shoulders
60
In adults brown adipose tissue is usually in
Kidney, adrenal glands , aorta, and mediastinum
61
The color of brown adipose tissue is because
Abundant mitochondria containing cytochrome pigment and blood capillaries in this tissue
62
Nuclei orientation in brown adipose tissue
Centrally located
63
Cells of Brown adipose tissue receive direct
Sympathetic innervation
64
Nerve impulse liberate to adipose brown tissue
Norepinephrine
65
Mitochondria in Brown adipose tissue have in their inner membrane much greater levels of transmembrane protein called
Thermogenin or uncoupling protein (UCP-1)
66
Permits the backflow of protons previously transported to the intermembranous space without passing through the ATP synthetase complexes
Thermogenin

HISTOLOGÍA (21 decks)

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