Adrenergic Agonists and Blockers (3)

Question 1

Alpha 1

Answer 1

INCREASE BP
VASODIALATION
increases cardiac contractility
dilates pupils
urinary bladder relaxation
contraction of prostate
ejaculation
dry mouth
blurred vision

Question 2

Effects of Adrenergic Agonists

Answer 2

Triggers fight or flight (sympathetic nervous system)

Question 3

Beta 1

Answer 3

INCREASES HR
increases cardiac contractility
increases renin secretion
increases bp

Question 4

Beta 2

Answer 4

BRONCHODIALATION
decreases GI tone and motility
increases blood flow in skeletal muscles
activates liver glycogenolysis
increases bloodsugar

Question 5

Vasodilation

Answer 5

increases blood flow to the vital organs

Question 6

Dopaminergic

Answer 6

located renal, mesenteric (around internal organs), coronary, and cerebral arteries

Question 7

Epinephrine Side Effects

Answer 7

cardiac dysrhythmias
tachycardia
dizziness
headache
sweating
insomnia
tremors
hyperglycemia

Question 8

Epinephrine drug interactions

Answer 8

beta-blockers (decrease epi action)
digoxin (cardiac dysrhythmias)
TCAs and MAOIs (intensify and prolong effects)

Question 9

Epinephrine Action

Answer 9

Adrenaline
Nonselective
Alpha1 increases the bp
beta1 increases hr
beta2 promotes bronchodilation
inotropic beta1 effects
vasoconstrictor
bronchodilator

Question 10

Epinephrine contraindications

Answer 10

cardiac dysrhythmias
hypertension
hyperthyroidism
diabetes
pregnancy

Question 11

Epinephrine uses

Answer 11

anaphylaxis
bronchospasms
cardiogenic shock
cardiac arrest

Question 12

Catecholamines

Answer 12

produce sympathetic response
endogenous (epi, norepi, dopamine)
synthetic (isoproterenol)

Question 13

noncatecholamines

Answer 13

Stimulate adrenergic receptors
longer duration than endogenous and synthetic (phenylephrine, albuterol)

Question 14

Direct acting

Answer 14

Directly stimulates the adrenergic receptor
(Epi, Norepi)

Question 15

indirect-acting

Answer 15

stimulates the release of norepinephrine from terminal nerve endings
(amphetamine)

Question 16

mixed- acting

Answer 16

stimulates adrenergic receptor sites and stimulates the release of norepinephrine from terminal nerve endings
(ephedrine)

Question 17

neurotransmitter inactivation

Answer 17

reuptake of transmitter back into neuron
enzymatic transformation or degradation
diffusion away from the receptor

Question 18

Drugs that halt the termination of neurotransmitters by inhibiting

Answer 18

norepi reuptake
norepi degradation

Question 19

Sympathetic Nervous System

Answer 19

Adrenergic
(Fight or flight)

Question 20

Adrenergic Response

Answer 20

dilate pupil
increase hr
bronchodilate
vasoconstriction
gi relaxation
bladder relaxation
uterus relaxation

Question 21

Albuterol (Proventil) action

Answer 21

selective
acts on beta2 adrenergic receptors
promotes bronchodialtion
PO, Inhaler, Nebulized

Question 22

Albuterol uses

Answer 22

treat bronchospasms
asthma
bronchitis
COPD

Question 23

Albuterol caution

Answer 23

severe cardiac disease
hypertension
hyperthyroidism
diabetes
pregnancy
renal dysfunction

Question 24

Albuterol side effects

Answer 24

tremors
dizziness
palpitations
tachycardia
cardiac dysrhythmias
restlessness
nervousness

Question 25

Albuterol drug interations

Answer 25

increase effects of sympathomimetics, MAO inhibitors, and tricyclic antidepressants antagonize effects of beta blockers

Question 26

Adrenergic Blockers/ antagonists

Answer 26

sympatholytics blocks the effects of adrenergic neurotransmitter block alpha and beta receptors

Question 27

types of adrenergic blockers

Answer 27

alpha-adrenergic antagonists 1. selective 2. non-selective beta-adrenergic antagonists 1. selective 2. non-selective

Question 28

effects of adrenergic blockers (alpha 1)

Answer 28

vasodilation ortho hypotension pupil constriction suppresses ejaculateation reduces the contraction of smooth muscles reduces contraction of bladder

Question 29

effects of adrenergic blockers (beta 1)

Answer 29

reduces cardiac contractility decreases pulse

Question 30

effects of adrenergic blockers (beta 2)

Answer 30

bronchoconstriction contracts uterus inhibits glycogenolysis

Question 31

alpha blockers

Answer 31

drugs that inhibit response at alpha-adrenergic receptor selective (block alpha 1) non-selective (block alpha 1 and 2) promotes vasodilation decreases symptoms of hypertrophy and vascular disease

Question 32

beta-blockers

Answer 32

decrease bp and pulse nonselective (beta 1 and 2) usually ends in lol used for angina, hypertension, heart failure selective (beta 1 only)

Question 33

side effects of beta blockers

Answer 33

bradycardia hypotension headaches drowsiness dizziness gi distress fainting depression

Question 34

Adrenergic neuron blockers

Answer 34

inhibit release of norepi at synapse decrease bp resperine (can cause vivid dreams) adrenergic neuron blockers sodium and water retention peripherally acting sympatholytics