Adrenergic Drugs

Question 1

How does epinephrine effect cardiac function?

Answer 1

increases the force of contraction (positive inotropic effect), increases heart rate, increases conduction velocity at the AV node

Question 2

how does epinephrine effect the vascular tone?

Answer 2

increases systolic BP; decreases diastolic BP and total peripheral vascular resistance; MAP remains unchanged

Question 3

what receptor type is responsible for the epinephrine effects of cardiac function?

Answer 3

beta 1

Question 4

what receptor types are responsible for epinephrine effects on vascular tone of skin vessels and mucous membranes?

Answer 4

mostly alpha 1

Question 5

what receptor types are responsible for epinephrine effects on vascular tone of skeletal muscle?

Answer 5

alpha 1 and beta 2

Question 6

what receptor types are responsible for epinephrine effects on vascular tone in renal and cerebral arteries?

Answer 6

D1 and alpha 1

Question 7

what are the effects of epinephrine on the respiratory system?

Answer 7

relaxes bronchial muscle and decreases bronchial secretion and congestion within bronchial mucosa

Question 8

how does epinephrine effect skeletal muscle?

Answer 8

causes muscle tremor and increases K+ uptake by skeletal muscle

Question 9

what effect does epinephrine have on blood glucose levels?

Answer 9

elevates blood glucose levels by enhancing liver glycogenolysis and gluconeogenesis

Question 10

what effect does epinephrine have on fee fatty levels?

Answer 10

increases it

Question 11

what effect does epinephrine have on renin?

Answer 11

it increases renin release

Question 12

which receptor is responsible for epinephrine causing relaxation of the bronchial muscle?

Answer 12

beta 2

Question 13

which receptor is responsible for epinephrine causing a decrease in bronchial secretion and congestion within bronchial mucosa?

Answer 13

alpha 1

Question 14

which receptor is responsible for epinephrine causing muscle tremors?

Answer 14

beta 2

Question 15

which receptor is responsible for epinephrine causing an increase in K+ uptake by skeletal muscle?

Answer 15

beta 2

Question 16

which receptor is responsible for epinephrine causing elevated blood glucose levels?

Answer 16

beta 2

Question 17

which receptor is responsible for epinephrine causing increase renin release?

Answer 17

beta 1

Question 18

what are the effects of norepinephrine on the heart?

Answer 18

reduces HR

Question 19

what is the effect of norepinephrine on vessels?

Answer 19

vasoconstrictor

Question 20

what effect does norepinephrine have on blood pressure?

Answer 20

increases systolic blood pressure and increases diastolic blood pressure

Question 21

what effect does norepinephrine have on peripheral vascular resistance?

Answer 21

increases

Question 22

what effect does epinephrine have on peripheral vascular resistance?

Answer 22

decreases it

Question 23

what are the effects of phenylephrine?

Answer 23

mydriatic and decongestant; causes severe vasoconstriction, blood pressure elevation, and severe bradycardia

Question 24

what are the effects of clonidine?

Answer 24

central effect on presynaptic alpha 2 receptors in the lower brainstem area: decreasing sympathetic outflow, reduction in blood pressure, and bradycardia