Shock drugs crossword

Question 1

characteristic of aortic dissection that makes it an emergency, otherwise an urgency?

Answer 1

ascending

Question 2

if this is in the venous blood, it can cause obstructive shock

Answer 2

fat

Question 3

other than for anaphylactic shock, this tends to be the best ionotropic/vasoconstrictor agent for treating shock

Answer 3

norepinephrine

Question 4

used in addition to jugular venous distention to pinpoint the cause of hypotension and guide its treatment

Answer 4

lung sound

Question 5

the alpha one agonist administered if there is a need for vasoconstriction when beta1 stimulation causes arrhythmias or TPR remains low during beta 1 stimulation

Answer 5

phenylephrine

Question 6

selectively dilates the venous side of the circulation; useful if hypertensive emergency is associated with acute pulmonary edema

Answer 6

nitroglycerin

Question 7

drug class used to treat the pain and inflammation of pericarditis

Answer 7

NSAIDs

Question 8

blocks microtubule formation, useful in treating acute and recurrent pericarditis because it disrupts the leukocyte infiltration of the pericardium

Answer 8

colchicine

Question 9

lactic acid build up when tissue lacks oxygen causes this

Answer 9

acidosis

Question 10

what could cause hypertensive emergency?

Answer 10

acute ischemic stroke

Question 11

intracellular form of this occurs when cells are anoxic

Answer 11

edema

Question 12

what is a potential adverse effect of anaphylactic shock?

Answer 12

coronary vasoconstriction

Question 13

potential adverse effect of shock; can also cause hypertensive emergency

Answer 13

acute kidney failure

Question 14

toxicity (irreversible neurologic changes, cardiac arrest) associated with prolong use of nitroprusside to control blood pressure, thiosulfate is the antidote

Answer 14

cyanide

Question 15

early non-selective alpha adrenergic blocker with short half life that still has use during hypertensive emergencies caused by catecholamine excess

Answer 15

phentolamine

Question 16

ultra-short acting dihydropyridine CCB used for hypertensive emergencies

Answer 16

clevidipine

Question 17

attempting to keep a patient with this includes using drugs (e.g. esmolol and labetalol) to lower heart rate to less than 60 bpm and SBP to 100-120

Answer 17

aortic dissection

Question 18

along with mixed venous oxygen tension, this is generally increased during the early “hyperdynamic” phase of septic shock due to the fall in systemic vascular resistance

Answer 18

cardiac output

Question 19

if hypertensive emergency due to an intracranial hemorrhage, what should you do?

Answer 19

use IV drugs to lower BP to less than 220 but not less than 140

Question 20

IV formulation of an ACEi administered orally as a prodrug, this can be useful when the underlying cause of a hypertensive emergency leads to high levels of renin secretion (e.g. acute unilateral renal stenosis)

Answer 20

enalaprilat

Question 21

non-adrenergic vasoconstrictor used as adjunct therapy in shock

Answer 21

vasopressin

Question 22

causes respiratory distress, tracheal deviation, and decreased venous return leading to obstructive shock

Answer 22

tension pneumothorax

Question 23

dilates arterial and venous circulation, given IV, short half life allows hypertensive effect to be controlled with dial

Answer 23

nitroprusside

Question 24

preferentially stimulates beta 1 receptors in the heart to increased cardiac output if needed when treating shock, but also see some stimulation of peripheral beta-2 receptors

Answer 24

dobutamine

Question 25

refers to the hypertensive crisis that can occur with the use of cocaine, amphetamines, etc., or with the abrupt discontinuation of alpha 2 agonists or beta blockers after a period of use to control blood pressure

Answer 25

sympathomimetic

Question 26

adverse effect seen with anaphylactic shock that is treated with epinephrine but not norepinephrine

Answer 26

bronchoconstriction

Question 27

agent that stimulates beta receptors at lower doses and both alpha and beta receptors at higher doses; no evidence of meaningful renal sparing from vasoconstrictor effects because of D1 receptor stimulation

Answer 27

dopamine

Question 28

how does pericarditis appear on EKG?

Answer 28

PR depression and concave ST elevation in multiple leads

Question 29

alpha/beta blocker used for hyperadrenergic hypertensive emergencies

Answer 29

labetalol

Question 30

what type of shock shows benefit of corticosteroid use?

Answer 30

septic shock

Question 31

can cause obstructive shock due to right ventricular compression

Answer 31

cardiac tamponade

Question 32

arterial vasodilator with unclear mechanism of action, used in hypertensive emergencies (pre-eclampsia) and also noteworthy for ability to cause drug-induced lupus syndrome

Answer 32

hydralazine

Question 33

benzodiazipine structure (an anxiolytic drug class) this drug is however a dopamine-1 receptor agonist that can be used to lower blood pressure during hypertensive emergencies

Answer 33

fenoldopam

Question 34

what would you use to treat aortic dissection if esmolol and labetalol were contraindicated or unavailable?

Answer 34

non-dihydropyridine CCBs

Question 35

short acting beta blocker that can be used in hypertensive emergencies. contraindications include bradycardia and decompensated heart failure

Answer 35

esmolol