Adrenergic Drugs Flashcards Preview

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Flashcards in Adrenergic Drugs Deck (24)
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1

epinephrine works on which receptors?

a1, a2, B1, B2

2

norepinephrine works on which receptors?

a1, a2, B1

3

ephedrine works on which receptors?

a1, a2, B1, B2

4

dopamine works on which receptors?

- low dose
- intermediate dose
- high dose

- D1 = D2
- D1 = D2 + B1
- D1 = D2 + B1 + a1

5

tyramine (found in wine and cheese)

mixed

6

ADE of tyramine

5-HT syndrome if on MAOI

7

ADE of norepinephrine

reflex bradycardia

8

isoproterenol works on which receptors?

B1, B2 ONLY

9

dobutamine works on which receptors?

B1 ONLY

increases contractions WITHOUT increasing HR

10

albuterol/salmeterol work on which receptors?

B2

11

terbutaline works on which receptors?

B2

12

ritodrine works on which receptors?

B2

13

ADE of albuterol/salmeterol

palpitations, tachycardia, hyperglycemia

14

clonidine works on which receptors?

a2 AGONIST

15

clonidine MOA

decreases presynaptic Ca++ levels in a2 R's of brainstem, inhibiting NE release

16

apraclonidine works on which receptors?

a2 AGONIST

17

a-methyldopa works on which receptors?

a2 AGONIST

18

ADE of clonidine

sexual dysfunction

19

ADE of a-methyldopa

hemolytic anemia (+ Coombs test)

20

phenylephrine works on which receptors?

a1 AGONIST

21

ADE of phenylephrine

rebound congestion, HTN

22

cocaine works on which receptors?

a1, a2

23

what is a unique characteristic of cocaine?

it is the ONLY inherent vasoCONSTRICTOR

24

MOA of amphetamines

- stimulates monoamines (NE, dopamine, and 5-HT)
- blocks catecholamine reuptake