Adrenergic Drugs Flashcards Preview

Pharmacology > Adrenergic Drugs > Flashcards

Flashcards in Adrenergic Drugs Deck (24)
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1
Q

epinephrine works on which receptors?

A

a1, a2, B1, B2

2
Q

norepinephrine works on which receptors?

A

a1, a2, B1

3
Q

ephedrine works on which receptors?

A

a1, a2, B1, B2

4
Q

dopamine works on which receptors?

  • low dose
  • intermediate dose
  • high dose
A
  • D1 = D2
  • D1 = D2 + B1
  • D1 = D2 + B1 + a1
5
Q

tyramine (found in wine and cheese)

A

mixed

6
Q

ADE of tyramine

A

5-HT syndrome if on MAOI

7
Q

ADE of norepinephrine

A

reflex bradycardia

8
Q

isoproterenol works on which receptors?

A

B1, B2 ONLY

9
Q

dobutamine works on which receptors?

A

B1 ONLY

increases contractions WITHOUT increasing HR

10
Q

albuterol/salmeterol work on which receptors?

A

B2

11
Q

terbutaline works on which receptors?

A

B2

12
Q

ritodrine works on which receptors?

A

B2

13
Q

ADE of albuterol/salmeterol

A

palpitations, tachycardia, hyperglycemia

14
Q

clonidine works on which receptors?

A

a2 AGONIST

15
Q

clonidine MOA

A

decreases presynaptic Ca++ levels in a2 R’s of brainstem, inhibiting NE release

16
Q

apraclonidine works on which receptors?

A

a2 AGONIST

17
Q

a-methyldopa works on which receptors?

A

a2 AGONIST

18
Q

ADE of clonidine

A

sexual dysfunction

19
Q

ADE of a-methyldopa

A

hemolytic anemia (+ Coombs test)

20
Q

phenylephrine works on which receptors?

A

a1 AGONIST

21
Q

ADE of phenylephrine

A

rebound congestion, HTN

22
Q

cocaine works on which receptors?

A

a1, a2

23
Q

what is a unique characteristic of cocaine?

A

it is the ONLY inherent vasoCONSTRICTOR

24
Q

MOA of amphetamines

A
  • stimulates monoamines (NE, dopamine, and 5-HT)

- blocks catecholamine reuptake