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ADRs Flashcards

1
Q

coronary vasospasm

A

cocaine, sumatriptan, ergot alkaloids, amphetamines

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2
Q

cutaneous flushing

A

Vanc, adenosine, niacin, Ca2+ channel blockers, echinocandins (“VANCE”)

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3
Q

dilated cardiomyopathy

A

anthracyclines (doxorubicin, daunorubicin)

prophylaxis: dexrazoxane

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4
Q

torsades de pointes (dIT)

A

Postassium Channel Blockers (III), Sodium channel blockers (IA), macrolides, haloperidol, choroquine, protease inhibitors

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5
Q

tordsades de pointes (FA)

A

antiArrythmics, antiBiotics, antipsychotics, antiDepressants (TCA), antiEmetics(ondansetron) (ABCDE)

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6
Q

adrenocortical insufficiency

A

HPA suppression 2* to glucocorticoid w/d

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7
Q

hot flashes

A

tamoxifen, clomiphene

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8
Q

hyperglycemia

A

tacrolimus, protease inhibitors, niacin, HCTZ, corticosteroids

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9
Q

hypothyroidism

A

lithium, amiodarone, sulfonamides

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10
Q

acute cholestatic hepatitis, jaundice

A

emycin

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11
Q

focal to massive hepatic necrosis

A

Halothane, amanita phalloide, valproic acid, acetaminophen

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12
Q

hepatitis

A

Isoniazid, pyrazinamide, statins, fibrates

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13
Q

pancreatitis

A

Didanosine, corticosteroids, alcohol, valproic acid, azathioprine, diuretics

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14
Q

pill-induced esophagitis

A

tetracyclines, bisphosphonates, KCl

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15
Q

pseudomembranous colitis

A

clindamycin, ampicillin, cephalosporins

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16
Q

cholinesterase inhibitor toxicity sx

A

diarrhea, urination, myosis, bradychardia, bronchospasm, excitation of sk m/CNS, lacrimation, sweating, salivation

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17
Q

hypertensive crisis

A

MAOI + tyramine (alcohol, cheese)

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18
Q

agranulocytosis

A

clozapine, carbamazepine, propylthioruracil, methimazole, colchicine, ganciclovir

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19
Q

aplastic anemia

A

carbamazepine, methimazole, NSAIDS, benzene, chloramphenicol, propylthiouracil

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20
Q

direct coombs positive hemolytic anemia

A

methyldopa, PCN

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21
Q

gray baby syndrome

A

chloramphenicol

22
Q

hemolysis in G6PD deficiency

A

Isoniazid, sulfonamides, dapsone, primaquine, aspirin, ibuprofen, nitrofurantoin, fava beans

23
Q

megoBLAStic anemia

A

phenytoin, methotrexate, sulfa drugs

“have a Blast w/ PMS”

24
Q

thrombocytopenia

A

heparin, cimetidine

25
thrombotic complications
OCPS, HRT
26
Fat redistribution
protease inhibitors, glucocorticoids | Fat PiG
27
gingival hyperplasia
phenytoin, ca2 channel blockers, cyclosporine
28
hyperuricemia
pyrazinamide, thiazides, furosemide, niacin, cyclosporine
29
myopathy
statins, niacin, colchicine
30
osteoporosis
corticosteroids, heparin
31
photosensitivity
Sulfonamides, Amiodarone, Tetracyclines, 5-FU "SAT For Photo"
32
Steven-Johnsons Sx
anti-epileptic drugs, allopurinol, sulfa drugs, PCN
33
SLE-like sx
sulfa drugs, hydralazine, isoniazid, procainamide, phenytoin "SHIPP"
34
teeth discoloration
tetracylcines
35
tendon issues
fluorquinolones
36
cinchonism
quinidine, quinine
37
parkinsonlike sx
antipsychotics, reserpine, metoclopramide
38
seizures
isoniazid (vit b6 deficiency), bupropion, imipenem/cilastatin, tramadol, enflurane
39
tardive dyskinesia
antipsychotics, metoclopramide
40
diabetes insipidus
lithium, demeclocycline
41
fanconi syndrome
tenofovir, ifosafamide expired tetracycline
42
heme cystitis
cyclophosphamide, ifosfamide,
43
interstitial nephritis
methicillin, NSAIDS, furosemide
44
SIADH
carbamazepine, cyclophosphamide, SSRI
45
dry cough
ACEI
46
pulmonary fibrosis
methotrexate, nitrofurantoin, carmustine, bleomycin, busulfan, amiodarone
47
antimuscarinic
atropine, TCA, H1-blockers, antipsych
48
disulfiram-like rxn
metronidazole, cephalosporin, griseofulvin, procarbazine, 1stgen sulfonylureas
49
nephrotoxicity/ototoxicity
aminoglycosides, vancomycin, loop diuretics, cisplatin
50
nephrotoxicity/neurotoxicity
aminoglycosides, cisplatin, polymixins
51
gynecomastia
"STACKED" Spirinolactone, Digoxin, Estrogens, Cimetidine, Alcohol (chronic), Ketoconazole, THC

step 1 pharm (8 decks)

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