Adult Rheuma Flashcards

(31 cards)

1
Q

What is osteoarthritis?

A

A progressive, degenerative joint disorder.

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2
Q

Which joints are most commonly affected by osteoarthritis?

A

Knees, followed by hips and hands.

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3
Q

Name a key symptom of osteoarthritis related to movement.

A

Reduced range of motion due to pain.

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4
Q

What are some typical signs on physical exam in OA?

A

Joint tenderness, crepitus, reduced movement.

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5
Q

How does OA pain typically change with activity and rest?

A

Worse with activity in later stages, may hurt after rest in early stages.

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6
Q

Is going up or down stairs more painful in OA?

A

Going down stairs is usually more painful.

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7
Q

What kind of weather tends to worsen OA symptoms?

A

Cold or damp weather.

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8
Q

How is OA diagnosed?

A

Primarily a clinical diagnosis.

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9
Q

Are CRP and ESR levels usually high or normal in OA?

A

They are typically normal.

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10
Q

What does the mnemonic ‘LOSS’ stand for in OA X-ray findings?

A

• Loss of joint space
• Osteophytes
• Subchondral sclerosis
• Subchondral cysts

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11
Q

What is the first-line treatment approach for OA?

A

Conservative management.

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12
Q

What is the first-line medication for OA?

A

Topical NSAIDs.

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13
Q

What are second-line options for OA pain?

A

Paracetamol and topical analgesics.

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14
Q

When are corticosteroid injections used in OA?

A

For acute pain flares when regular pain meds aren’t enough.

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15
Q

What is rheumatoid arthritis

A

A chronic, systemic inflammatory disease affecting synovial joints.

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16
Q

Which joints are most commonly affected in RA?

A

Small joints of the hands and feet, especially PIP, MCP, wrists, MTP, knees, ankles, cervical spine.

17
Q

Is RA joint pain usually symmetrical or asymmetrical?

18
Q

What systemic symptoms may occur in RA?

A

Fatigue and low-grade fever.

19
Q

What is a swan neck deformity?

A

Hyperextension of the PIP joint and flexion of the DIP joint.

20
Q

What is a boutonnière’s deformity?

A

Flexion of the PIP joint and hyperextension of the DIP joint.

21
Q

Name three other common deformities in RA.

A

Z thumb deformity, ulnar deviation, piano key wrist deformity.

22
Q

Name three extra-articular features of RA.

A

Dry eyes, pericarditis, pulmonary fibrosis. (More: scleritis, rash, nodules, anaemia, Raynaud’s, etc.)

23
Q

What type of anaemia is common in RA?

A

Normochromic, normocytic anaemia.

24
Q

What inflammatory markers are typically raised in RA?

25
Which antibody is more specific for RA: RF or anti-CCP?
Anti-CCP is more specific and sensitive in erosive disease.
26
What can uric acid or synovial fluid analysis help exclude?
Polyarticular gout.
27
What might an X-ray show in RA?
Joint erosions, used to differentiate from OA.
28
What are the first-line drugs in RA management?
DMARDs: methotrexate, sulfasalazine, leflunomide, hydroxychloroquine
29
Name two anti-TNF biologic agents used in RA.
Adalimumab and infliximab.
30
When are corticosteroids used in RA?
For short-term use during flares.
31
What is the role of NSAIDs in RA?
Pain relief, used cautiously due to side effects.