Affective Disorders Flashcards

(47 cards)

1
Q

define mood disorders

A

disorders of mental status and function where altered mood is the (or a) core feature

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2
Q

give two broad examples of mood disorders

A

depression

mania

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3
Q

what are the commonest group of mental disorders?

A

mood disorders

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4
Q

how can a mood disorder present?

A

primary problem

consequence of another disorder or illness

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5
Q

what are mood disorders often associated with?

A

anxiety symptoms and anxiety disorder

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6
Q

where people have both depression and anxiety, the focus is on the treatment of what?

A

depression

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7
Q

name and describe two classification systems for psychiatric conditions

A

ICD-10
o International Classification of Disease 10th Edition
o WHO
• DSM-5
o Diagnostic and Statistical Manual of Mental Disorders 5th Edition
o American Psychiatric Association

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8
Q

describe depression as a symptom

A

o An emotion within the range of normal experience
§ Describe a state or feeling, or mood that can range from normal experience
to severe, life threatening illness
§ A systemic symptom (complaint) with similarities to fatigue and pain
§ Typically considered as a form of sadness, not just an absence of happiness

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9
Q

describe depression as a syndrome

A

a constellation of symptoms and signs

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10
Q

describe depression as a recurrent illness

A

o Recurrent depressive disorder
o If they have it once they are likely to have a further episode
o If severe enough to require inpatient treatment, approximately 80% will have a
further episode

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11
Q

in psychiatry how may you decide when sadness becomes abnormal?

A
  1. Persistence of symptoms
  2. Pervasiveness of symptoms
  3. Degree of impairment
  4. Presence of specific symptoms or signs
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12
Q

depressive illness symptoms occur in 3 spheres, name them

A

psychological
physical
social

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13
Q

name two broad psychological symptoms of depression

A

change in mood

change in though content

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14
Q

describe change in mood in depression

A

o Depression – may find diurnal variation
o Anxiety – inability to relax
o Perplexity – particularly in puerperal illness (post-natal), bewildered or overwhelmed
o Anhedonia – not being able to experience pleasure in the things you would usually
enjoy

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15
Q

describe change in thought content in depression

A

o Guilt – unjustified
o Hopelessness
o Worthlessness
o Any neurotic symptomatology e.g. hypochondriasis, agoraphobia, obsessions +
compulsions, panic attacks
o Ideas of reference – connecting things around you to negative things about you e.g.
laughing at
o Delusions and hallucinations if severe – psychotic symptoms

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16
Q

name two broad physical symptoms of depression

A

change in bodily function

change in psychomotor functioning

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17
Q

what changes in bodily function may a person suffering from depression experience?

A
o Energy – fatigue
o Sleep – often insomnia, not being able to get to sleep, disturbed sleep, early waking
o Appetite – weight loss
o Libido
o Constipation
o Pain
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18
Q

what changes in psychomotor function may a person suffering from depression experience?

A

agitation

retardation

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19
Q

list the social symptoms of depression

A
  • Loss of interests
  • Irritability
  • Apathy
  • Withdrawal, loss of confidence, indecisive
  • Loss of concentration, registration and memory
20
Q

Describe the ICD-10 classification of depression

A

• Last for at least 2 weeks
• No hypomanic or manic episodes in lifetime
• Not attributable to psychoactive substance use or organic mental disorder
• If psychotic symptoms or stupor then severe depression with psychotic symptoms
o Need to exclude other psychotic illnesses first like schizophrenia

21
Q

Describe the ICD-10 classification of somatic syndrome

A

Somatic syndrome is a marked loss of interest or pleasure in activities that are normally pleasurable. There is a lack emotional reactions to events or activities that normally produce an emotional
response. Patients often wake 2 hours before the normal time and find that the depression is worse in the morning. Objective evidence of psychomotor agitation or retardation. Marked loss of appetite with weight loss (5% + of body weight in a month). Often marked loss of libido.

22
Q

Describe the ICD-10 classification of mild depression

A

• General criteria
• At least 2 of:
o Depressed mood that is abnormal for most of the day almost every day for the past
two weeks, largely uninfluenced by circumstances
o Loss of interest or pleasure
o Decreased energy or increased fatigability
• Additional from this list to give at least 4
o Loss of confidence or self esteem
o Unreasonable feelings of guilt or self-reproach or excessive guilt
o Recurrent thoughts of death by suicide or any suicidal behaviour
o Decreased concentration
o Agitation or retardation
o Sleep disturbance of any sort
o Change in appetite

23
Q

Describe the ICD-10 classification of moderate depression

A

• General criteria
• At least 2 of:
o Depressed mood that is abnormal for most of the day almost every day for the past
two weeks, largely uninfluenced by circumstances
o Loss of interest or pleasure
o Decreased energy or increased fatigability
• Additional from this list to give at least 6
o Loss of confidence or self esteem
o Unreasonable feelings of guilt or self-reproach or excessive guilt
o Recurrent thoughts of death by suicide or any suicidal behaviour
o Decreased concentration
o Agitation or retardation
o Sleep disturbance of any sort
o Change in appetite

24
Q

Describe the ICD-10 classification of severe depression

A

• General criteria
• All of:
o Depressed mood that is abnormal for most of the day almost every day for the past
two weeks, largely uninfluenced by circumstances
o Loss of interest or pleasure
o Decreased energy or increased fatigability
• Additional from this list to give at least 8
o Loss of confidence or self esteem
o Unreasonable feelings of guilt or self-reproach or excessive guilt
o Recurrent thoughts of death by suicide or any suicidal behaviour
o Decreased concentration
o Agitation or retardation
o Sleep disturbance of any sort
o Change in appetite

25
for how long following child birth is there an increased risk of psychiatric admission
first 30 days | continues for 24 months
26
what percentage of women experience the baby blues within 2 weeks of giving birth?
75%
27
how many women develop MDD within 3-6 months of giving birth?
10%
28
how common is puerperal psychosis and what is the risk of recurrence in subsequent deliveries?
1 in 500 | 1 in 3
29
list the differential diagnoses for depression
* Normal reaction to life event * SAD * Dysthymia * Cyclothymia * Bipolar * Stroke, tumour, dementia * Hypothyroidism, Addison’s, hyperparathyroidism * Infections – influenza, infectious mononucleosis, hepatitis, HIV/AIDS * Drugs
30
what groups of treatment can be used for depression?
antidepressants psychological treatments physical treatments
31
name some classes of antidepressants
SSRIs SNRIs TCAs MOIs
32
list psychological treatments for depression
CBT IPT Individual dynamic psychotherapy Family therapy
33
list physical treatments for depression
ECT Psychosurgery Deep brain stimulation vagus nerve stimulation
34
name 2 measurement tools in depression
* SCID (Structured Clinical Interview for DSM disorders) | * SCAN (Schedules for Clinical Assessment in Neuropsychiatry)
35
define mania
a state of feeling, or mood, that can range from a near normal experience to severe, life-threatening illness. It is rarely a symptom, often associated with grandiose ideas, disinhibition, loss of judgement; with similarities to the mental effects of stimulant drugs (AMPH, cocaine). Typically considered as a form of pathological, inappropriate elevated mood. Lack of insight.
36
in psychiatry how may you decide between what is mania and what is not?
* Persistence of symptoms * Pervasiveness of symptoms * Degree of impairment * Presence of specific symptoms or signs
37
describe hypomania
• Lesser degree of mania, no psychosis • Mild elevation of mood for several days on end • Increased energy and activity, marked feeling of wellbeing • Increased sociability, talkativeness, overfamiliarity, increased sexual energy, decreased need for sleep • May be irritable • Concentration reduced, new interests, mild overspending • Not to the extent of severe disruption of work or social rejection
38
describe mania with or without psychosis
* 1 week, severe enough to disrupt ordinary work and social activities more or less completely * Elevated mood, increased energy, overactivity, pressure of speech, decreased need for sleep * Disinhibition * Grandiosity * Alteration of senses * Extravagant spending * Can be irritable rather than elated
39
list the psychiatric differentials for mania
``` o Mixed affective state o Schizophrenia disorder o Schizophrenia o Cyclothymia o ADHD o Drugs and alcohol ```
40
list the medical differentials for mania
o Stroke, MS, tumour, epilepsy, AIDS, neurosyphilis o Endocrine – Cushing’s, hyperthyroidism o SLE
41
what tools can be used to measure symptoms in mania
SCID SCAN Young Mania Rating Scale (YMRS)
42
list the types of treatments for mania
Antipsychotics Mood stabilisers Lithium ECT
43
list the antipsychotics that could be used for mania
olanzapine risperidone quetiapine
44
list the mood stabilisers that could be used for mania
sodium valproate lamotrigine carbamazepine
45
what is bipolar disorder?
Bipolar affective disorder consists of repeated (2+) episodes of depression and mania or hypomania. If no mania or hypomania then a diagnosis of recurrent depression is given. If there is no depression then a diagnosis of hypomania or bipolar disorder is made. In DSM-5 a single episode of mania is sufficient to diagnose bipolar disorder (because there is an assumption you’ve also had depressive episodes).
46
describe the clinical course of major depression
* Typical episode lasts 4-6 months * 54% recovered at 26 weeks * 12% fail to recover * 80+% have further episodes * 15% die by suicide
47
describe the clinical course of bipolar disorder/mania
* Typical manic episode lasts 1-3 months * 60% recovered at 10 weeks * 5% fail to recover * 90% have further episodes * 1/3 have poor outcome * 1/3-1/4 have good outcome * 10% die by suicide