Ageing Flashcards
(10 cards)
1
Q
Lifespan
A
Period of time in which life events of a species occur
2
Q
Life expectancy
A
Avg time a person can expect to live based on DOB, current age and sex
3
Q
Mortality shock
A
Sudden + unexpected event causing a temporary spike in death rates
4
Q
Atherosclerosis
A
Thickening of artery walls
WBC influx + proliferation of smooth muscle cells
Atheromatous (fibrofatty) plaque
5
Q
Hutchinson-Gilford progeria
A
Mutation in LMNA
Production of defective lamin A (progerin)
Usually forms nuclear envelope filaments
Causes nuclear envelope defects + impaired DNA repair
6
Q
Werners (adult onset) progeria
A
Autosomal recessive
WRN gene mutation (DNA helicase)
Usually used in telomere replication + interaction with nuclear lamina
Fewer cell divisions + telomere replication impaired
7
Q
Downs syndrome
A
8
Q
A
9
Q
A
10
Q
A
