Agents used in Dyslipidemia Flashcards

(28 cards)

1
Q

problem with lipid levels in the blood

A

Dyslipidemia

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2
Q

complexes that transport plasma lipids

A

lipoproteins

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3
Q

6 types of lipoproteins

A
  1. chylomicrons
  2. very low-density lipoproteins
  3. Intermediate-density lipoproteins
  4. low-density lipoproteins
  5. high-density lipoproteins
  6. apolipoproteins
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4
Q

lipids are made up of

A

cholesterol and TAGs

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5
Q

site of cholesterol synthesis

A

Liver

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6
Q

T/F: 95% of diet contain TAGs

A

True

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7
Q

largest lipoprotein that transports TAGs and cholesterol from diet

A

chylomicrons

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8
Q

Where do chylomicrons transport TAGs and cholesterol to?

A

adipose tissues

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9
Q

content of chylomicron remnants

A

cholesterol

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10
Q

T/F: Chylomicron remnants are also called “cholesterol-rich chylomicron remnants”

A

True

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11
Q

chylomicron remnants are transported where?

A

liver

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12
Q

counterpart of chylomicron that carries TAGs and cholesterol

A

VLDL

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13
Q

carry cholesterol to the liver and is a source of LDL

A

IDL

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14
Q

removes excess cholesterol from tissue and transport it back to the liver

A

HDL

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15
Q

Disorders of lipid and lipoprotein metabolism

A

Dyslipidemia

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16
Q

Characterized by lipid abnormalities

17
Q

lipid abnormalities include …

A
  1. Elevated triglycerides
  2. Elevated low density lipoprotein (LDL)
  3. Elevated total cholesterol (TC)
  4. Reduced high density lipoprotein (HDL)
18
Q

Etiology of dyslipidemia`

A
  1. Primary causes
  2. Secondary causes
19
Q

dyslipidemia caused by genetics

A

primary cause

20
Q

dyslipidemia caused by lifestyle or disease

A

secondary cause

21
Q

secondary dyslipidemia is also called

A

acquired dyslipidemia

22
Q

T/F: secondary or acquired dyslipidemias can accompany genetic disorders

23
Q

acquired dyslipidemias accompanied by genetic disorders may be associated with …

A
  1. diet
  2. medication
  3. comorbid conditions
24
Q

acquired dyslipidemias accompanied by genetic disorders associated with excessive alcohol use, anorexia, weight gain, excessive intake of carbohydrates or saturated fat

25
acquired dyslipidemias accompanied by genetic disorders associated with progestins, thiazide diuretics, glucocorticoids, β-blockers, isotretinoin, protease inhibitors, cyclosporine, mirtazapine, sirolimus
medicaiton
26
acquired dyslipidemias accompanied by genetic disorders associated with nephrotic syndrome, renal failure, hypothyroidism, obesity, diabetes
comorbid conditions
27
T/F: Dyslipidemia is asymptomatic
True
28