Aging Flashcards

(42 cards)

1
Q

aged

A

65>

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2
Q

habits that incr life expectancy and number of quality years

A
  • no smoking
  • moderate alcohol consumption
  • no snacking
  • maintain proper weight
  • daily breakfast
  • 7-8 hours sleep
  • regular exercise
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3
Q

exercise decreases risk of

A

cardiovascular disease
cancer
osteoporosis
etc

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4
Q

active people live longer and have more quality years

A

active individuals have 20-50% lower overall mortality rates

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5
Q

effects of age on CV system after 25

A

VO2 max decreases by 10% per decade due to loss of muscle mass, physical activity, and aging

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6
Q

if active VO2 max is

A

similar between 65-75 year-olds and young adults

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7
Q

inevitable loss of CV fitness

A

decreased HR max, SV max, Q max, blood volume

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8
Q

effects of exercise for the aged

A

adaptions to properly designed endurance training in aged similar to those seen in YA
- VO2 max increases 20-50%

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9
Q

improvements of CV in aged vs YA

A

Aged
- emphasize greater caution and slower progression
- beginning - avoid high impact aerobic activity
- prefer low impact
- even if VO2 max not improved much, improved health by controlling risk factors and improving daily function

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10
Q

effects of age on muscle fitness

A

after 50 - muscle mass and strength decr by 10% per decade

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11
Q

strength loss causes

A

loss of muscle mass
- fiber atrophy and decreased number of fibers
- type II fibers preferentially lost - sharp decrease in muscle power increases fall risk

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12
Q

ability for elderly to function independently

A

related mostly to muscle fitness

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13
Q

benefits of resistance training

A
  • counter sarcopenia
  • improve neural activation in trained muscles
  • reduce risk factors
  • incr metabolic rate by adding muscle mass
  • decrease incidence of falls
  • decrease total and intra-abdominal fat
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14
Q

adaptation to resistance training aged and YA

A

strength incr by 60-100%

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15
Q

same exercise prescription between aged and YA BUT

A

less resistance, more reps, slower progression
emphasize proper technique to avoid injury

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16
Q

summary of exercise for the aged

A
  • same FITT and expected improvements
  • focus on fall prevention
  • proper cool down
  • direct supervision may be warrented
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17
Q

sarcopenia

A

age-related loss of skeletal muscle mass two standard deviations below the mean

18
Q

dynapenia

A

age-related loss of muscular strength
- faster than sarcopenia
- related to change in muscle quality

19
Q

decline in muscle mass begins around 50

A

slower rate of protein synthesis
- rate of decline speeds up at 60 when denervation begins

20
Q

metabolic syndrome

A

present w/ 3 out 5
1. elevated waist circumference
2. elevated triglycerides
3. low HDL
4. high blood pressure
5. fasting blood glucose greater than 100 mg/dL

21
Q

inflammaging

A

upregulation of inflammatory response that occurs w/ advancing age contributes to sarcopenia and other ailments

22
Q

sarcopenia rates

A

cross-sectional studies - 0.8% annually
longitudinal studies - 1.4 % annually

23
Q

lower vs upper limb sarcopenia

A

effect greater in lower limbs

24
Q

FT fibers vs ST fibers sarcopenia

A

FT suffer greater atrophy than ST fibers

25
loss of mass equals
loss of strength and power - power happens first and more severely (associated w/ accidental falls)
26
specific tension sarcopenia
declines in isolated myofibers but not at whole muscle level
26
muscular endurance sarcopenia
may or may not be effected - decrease in endurance best explained by changes in neural activation rather than contractile aparatus
27
atrophy is fiber type specific in sarcopenia
no significant loss of CFA in type 1 - 13% decrease in Type IIA - 24% decrease in Type IIX
28
cellular atrophy
due to changes in body's hormone/cytokine milleu - related to fiber type specific declines in mRNA for myosin
29
changes in fiber type distribution
greater portion of whole muscle comprised of ST - greater clustering of fiber types - decreased ability of MN to sprout lengthy terminal branches - greater number of hybrid fibers - more denervation and re-innervation
30
age related denervation
decreased number of motor units - remaining motor units larger w increased metabolic demand - greater loss of FT
31
gradual decay of NMJ
precedes MU remodeling - FT NM show deterioration first - due to mitochondrial dysfunction and oxidative stress or impaired autophagy
32
dementia
cognitive decline severe enough to interfere w/ ability to live independently - problem of declining cerebral blood flow
33
dementia risk factors
diabetes, social isolation, physical inactivity, depression, smoking, hearing loss, etc
34
regular exercise impact on cognition
positive impact on aged with MCI - increased brain volume increased blood blow to brain, BDNF, hippocampal neurogenesis
35
ALD
activities of daily living
36
dementia starting point
mild cognitive impairment - 20% of aged display MCI - 15% of that will progress to Alzheimer's - link to vascular disease
37
aerobic exercise and dementia
promotes blood flow to brain - increase vessel ability to dilate - decreases incidence of dementia
38
resistance training and cognitive function
increases cognitive function but little impact on memory
39
exercise pairs w ADL over 6 months
showed most pronounced improvements than either by itself
40
combine cognitive training with aerobic training
most effective in performance of ADL, global cognitive function, and mood
41
testing on those with memory impairment (not dementia)
- simultaneous aerobic and memory training - increased memory and attention duration - sequential training - improved executive function