Alcohol Use disorder Flashcards

(32 cards)

1
Q

What are the signs of alcohol withdrawal?

A

Hallucinations
autonimic=sweating, HR
Seizures

Anxiety

Psychomotor agitation
insomnia
nausea
tremor

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2
Q

When does AWS peak?

A

2-3 days

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3
Q

When does delirium tremens happen?

A

48 hrs to 96 hours

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4
Q

How can we predict alcohol withdrawal? What us a high risk score?

A

PAWSS score
>4

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5
Q

What drug do we use for seizures and delirium?

A

benzos

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6
Q

What can we do for the anxiety, hypertension and tachycardia?

A

clonidine

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7
Q

What only other medication MAY help with alcohol withdrawal seizures?

A

Phenobarbital

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8
Q

What drug for hallucinations?

A

haloperidol

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9
Q

Differences between benzos?

A

Lorazepam-shorter acting, takes a bit longer to work better for hepatic issues
lorazepam can be given IM, subcut

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10
Q

For CIWA what is moderate and severe?

A

> 10 needs treatment
Mod=>15
Severe=>20

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11
Q

When must you hold the benzo?

A

if SBP<90 or RR <10

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12
Q

What other supportive care for AWS?

A

thiamine- prevent wernicke
folate- anemia
multivitamin
electrolytes and fluids

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13
Q

Long term complications of Alcohol use?

A

hepatic, arrhythmia, HTN

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14
Q

Stages of thinking of quitting alcohol?

A

pre contemplation-no interest
contemplation-thinking
prep
Action
maintenance

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15
Q

AUD clinical markers

A

MCV>96
AST:ALT >2:1
GERD,HTN
Cog issues

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16
Q

Standard drink sizes?

A

can of beer
5 oz of wine
3 oz

17
Q

Canada guidlines for drinks?

A

0=best
<2=low risk

18
Q

How does naltrexone work?

A

blocks euphoric effects= prevents a lapse from relapse

19
Q

How does acamprosate work?

A

restore imbalance of GABA and glutamate

20
Q

When to use acamprosate over naltrexone?

A

bad liver or opioid use as well

21
Q

Which agent prevents lapse?

22
Q

Dose of acamprosate?

23
Q

How to dose naltrexone?

A

slowly due to gi upset

24
Q

Monitoring of naltrexone?

25
Monitoring of acamprosate?
renal
26
IS combo effective for AUD?
not any evidence
27
Duration of therapy for AUD?
Individualize
28
Is topiramate useful?
decreases craving by decrease DA release BUT bad brain fog
29
Is gabapentin useful?
lowers withdrawal symptoms
30
How does disulfiram work?
stops aldehyde dehydrogenase and blocks metabolism= BAD sweating, headache, nausea
31
Should we recommend disulfiram?
NO
32
When do you start disulfiram?
abstain from alcohol for 12 hours minimum