All Flashcards

(33 cards)

1
Q

Q: Hormones and Endocrine System - types

A

A: autocrine, paracrine, endocrine, neurocrine

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2
Q

Autocrine

A

Hormonal signal acts back on cell of origin

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3
Q

Paragons

A

Hormonal signal carried to adjacent cells over a short distance via interstitial fluid

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4
Q

Endocrine

A

Hormone signal released into bloodstream and carried to distant target cells

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5
Q

Neurocrine

A

Hormonal originates in neurone and after transport down avon released into bloodstream and carried to distant target cells

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6
Q

Hormones

A

Chemical messengers

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7
Q

Lipid Derived hormones

A

Not stored in cells, synthesised on demand from precursor lipids as lipids can diffuse through membrane
Steroid hormones formed from cholesterol
Steroid hormones transported in blood bound to serum proteins

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8
Q

Plants and graviperception

A
  • Carried out by statoliths
  • Shoots negatively gravitrophic
  • Roots positively gravitrophic
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9
Q

Transfer of heat energy

A

Conduction
Convection
Radiation
Evaporation

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10
Q

Plants and thermal environment - temp regulation

A

Transpiration
Colours
Hairs
Waxy cuticles
leaf shape
stoma

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11
Q

Ectothermic Animals

A

Use environment to raise body temperature

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12
Q

Endothermic Animals

A

Use metabolism to raise body temperature

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13
Q

Four major tissues in human body

A

Muscle
Connective
Epithelial
Nervous

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14
Q

Muscle Tissue

A

function - movement speaking chewing
muscles types - cardiac smooth and skeletal

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15
Q

Fast twitch muscles

A

sprints, use metabolism for fuel, provides short burst of speed, fires rapidly, fatigues more quickly

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16
Q

Short twitch

A

Marathon runner, use oxygen, continuous energy, endurance

17
Q

Skeletal Muscle Structure

A

Composed of specialised cells - myocytes
Characterised by protein filaments - actin and myosin

18
Q

Neuromuscular Transmission

A

1- Arrival of action potential
2- Depolarisation of presynaptic membrane and opening of voltage gated Ca channels
3-Increase of intracellular Ca leads to release of Ach from synaptic vesicles
4-Binding of Ach to its receptors on ligand-gated cation channels
5- Activation of Ach gated ion channels in the end plate membrane
6-Increase of Na and K conductance via ligand gated no selective cation channels leads to generation of end plate potential
7- Generation of the EPP leads to generation of action potential of electrically excitable skeleti
muscle sarcolemma

19
Q

Sliding filament model of muscle contraction

A

1- Rise of intracellular Ca2+
2-Binding of Ca2+ to troponin moves to tropomyosin away from myosin binding sites on actin
3- Cross bridge forms
4- Power stroke
5- Cross bridge detachment
6- Reactivation of myosin head
7- Repositioning of energized myosin head

20
Q

Types of muscle contraction

A

Isometric - no change of muscle fibre length, tension increased
Isotonic - tension stays same, length of fibres altered

21
Q

Nociception

A

Mechanism by which noxious peripheral stimuli are transmitted to CNS to elicit a mechanical response

22
Q

Nociception and Pain

A

Nociception - PNS and CNS process info about external and internal environment
Pain -complex sensory and emotional experience from higher brain processing

23
Q

Analgesic

A

Relieve pain due to single or specific pain syndromes

24
Q

Opioid drugs

A

substance the produces morphine like effects

25
Main routes of administration
Topical - on the skin Systemic - into the body GI tract Oral Rectal Injection IV inhalation
26
Nanoparticle drug delivery
Advantages - targeted delivery, shield from degradation Disadvantage- increased costs, require enhanced methods
27
Heart, Lung and Kidney Development - 1. Specification of heart fields
Controlled by fibronectin, BMP4, Noggin, and Wnt inhibition. Nkx2.5 gene essential.
28
2. Formation of heart tube
Midline migration; failure leads to cardia bifida. Zebrafish used as model.
29
3- Heart tube looping
Hox genes and left-right asymmetry guide structure. Defects cause situs in versus
30
Originates from intermediate kidney
pronoephros medonephros metaphors
31
Functions of the human kidney
Regulate blood pressure Stimulate synthesis of red blood cell Maintain calcium level Regulation of blood flow, ion conc, fluid regulation, waste removal
32
33
Mechanics of breathing
Breathing in - diaphragm contracts