Alpha and Beta

Question 1

How does alpha 1 agonist work?

Answer 1

A1–>vasoconstriction–> increase BP, decrease bleeding, mydriasis, decrease in nasal congestion

Question 2

Indication for alpha 1

Answer 2

Orthostatic hypotension
WL suppression
Injection for priapism
Ophthalmic for mydriasis in eye exam
Glaucoma
Decongestant
Stress Incontinence

Question 3

S/E/ A1

Answer 3

syncope, tachycardia, HTN

Question 4

Caution A1

Answer 4

HTN hx

Question 5

How does alpha 1 antagonist work?

Answer 5

block A1–> vasodilation–> relax prostate and bladder neck

Question 6

Indication alpha 1 antagonist

Answer 6

BPH with HTN

Question 7

S/E alpha 1 antagonist

Answer 7

orthostatic hypotension, dizziness, reflex tachycardia, nasal congestion, sexual dysfunction

Question 8

How does A2 agonist work?

Answer 8

stimulate central A2–> decrease SNS

Question 9

Indication A2 agonist

Answer 9

HTN

Question 10

S/E A2 agonist

Answer 10

dry mouth, sedation, fatigue, postural hypotension

Question 11

Methyldopa S/E

Answer 11

autoimmune hemolytic anemia

Question 12

How does non-selective alpha antagonist work?

Answer 12

block A1 and A2–> antihypertensive b/c vasodilation

Question 13

Indication non-selective alpha antagonist

Answer 13

pheochromocytoma and epic pen reversal

Question 14

S/E non-selective alpha antagonist

Answer 14

orthostatic hypotension, dizziness, reflex tachycardia, nasal congestion, D/N/V, priapism, peptic ulcer, MI, stroke, arrhythmia

Question 15

How does beta 1 agonist work?

Answer 15

positive inotrope, stimulate kidney and heart, increase renin release and renal BF

Question 16

Indication B1 agonist

Answer 16

severe CHF, stress test

Question 17

S/E B1

Answer 17

tachycardia

Question 18

How does beta 2 agonist work?

Answer 18

stimulate B2–> bronchodilator and uterine relaxation

Question 19

Indication B2

Answer 19

COPD/asthma
delay premature labor
priapism

Question 20

Patho Beta Block

Answer 20

Block beta–>decrease CO, HR and contractility; decrease renin secretion; decreasepost-MI ventricular remodeling

Question 21

Indication BB

Answer 21

HTN
Class 2 tachyarrhythmia
HF
Angina
Acute MI
migraine prophylaxis 
thyrotoxicosis with palpitation
acute angle glaucoma
benign essential tremor

Question 22

Caution with BB

Answer 22

DM b/c mask hypoglycemia
Asthma/COPD (nonselective agents)
2nd/3rd Heart block
Cocaine induced MI
decompensated HF
worsens PVD and Raynaud

Question 23

How does A1 antagonist help cholesterol

Answer 23

increase HDL and lower LDL

Question 24

Methyldopa cannot be used with

Answer 24

MAOI inhibitor