Autonomic drug information

Question 1

norepinephrine

Answer 1

affect alpha 1 to increase BP for acute hypotension and cardiac arrest

Question 2

epi

Answer 2

alpha and beta affected

For PEA, cardiac arrest, asthma, COPD, anaphylaxis, local anesthetic

Question 3

Dopamine

Answer 3

low dose–> renal vasodilation via D1

High dose–> B1 activation for HR and contractility and A1 for vasoconstriction (shock and severe CHF)

Question 4

SLUDD-C

Answer 4

salivation, lacrimation, urination, defecation, digestion, pupil constriction

Question 5

Direct muscarinic agonist

Answer 5

stimulate PNS via muscarinic ACh receptors in peripheral tissue

Question 6

Indirect cholinergic agonist

Answer 6

blocks acetylcholinesterase at nicotinic and muscarinic

Question 7

Indication direct muscarinic agonist

Answer 7

acute angle glaucoma
post op ileus
post part urinary retention
dry mouth

Question 8

C/I direct muscarinic agonist

Answer 8

CVD and asthma

Question 9

Indication Indirect cholinergic agonist

Answer 9

MG, alzheimers, glaucoma, antidote for atropine

Question 10

Treat organophosphate toxicity

Answer 10

atropine and pralidoxime

Question 11

Indication direct muscarinic antagonist

Answer 11

COPD
bradycardia
motion sick
parkinson
urge incontinence
diarrhea

Question 12

C/I direct muscarinic antagonist

Answer 12

acute narrow angle glaucoma, BPH with urine retention

Question 13

Depolarizing nicotinic antagonist

Answer 13

produce persistent depolarization–> skeletal muscle resistant to Each activation

Question 14

Nondepolarizing nicotinic antagonist

Answer 14

block nicotinic receptor. neurotransmission in skeletal muscle–> decrease ACh–> skeletal muscle paralysis

Question 15

Indication nicotinic antagonist

Answer 15

muscle relax in surgery and intubation

Question 16

S/E nicotinic antagonist

Answer 16

hypotension, respiratory arrest