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Anti-VEGF treament > AMD > Flashcards

Flashcards in AMD Deck (15):
1

What bed corrected acuity must you have to be eligible for NICE treatment?

6/12 - 6/96

2

Apart from va what other criteria are required to benefit from NICE approved treatment ?

  • No permanent structural change to fovea
  • Evidence of disease progression (reduced va, blood vessel growth verified by FFA) 
  • Lesion size less than 12 disc area in greatest linear dimension

3

What is the Eylea loading dose regime?

3 x monthly

3 x two monthly

4

At the seventh visit with Eylea if oct fluid increases or va reduces what is the management?

Inject and reduce follow up to 6 weeks.

5

A patient has had 3 x 12 weekly injections and is still dry what is the management?

Discharge to stable clinic.

6

With Lucentis what happens after initial 3 monthly loading dose?

Patient may be switched to PRN basis if dry. If they reactivate a treat and extend protocol could be followed.

7

A patient is switched from lucentis having received more than 7 injections in last 12 visits. What Eylea protocol should she be started on?

3 x two monthly injections then follow Eylea protocol as per 7th visit.

8

If a patient is responding poorly to Eylea at 3rd visit what is management?

Consider switch to Lucentis

9

At what point does NICE consider cessation of therapy due to failure?

If va has dropped by >30 letters despite treatment or vision drops to <15 letters caused only by amd lesion. Treatment should be withheld permanently.

10

What are the benefits of treatment?

95% achieve stability of visual acuity and in 30% increase V/a

11

What is the risk of complete visual loss?

1:1000

12

What systemic risks are there to anti-vEGF?

MI or stroke

13

What is the rate of retinal tear?

1 in 8000

14

What is the rate of retinal detachment?

1 in 50000

15

When do patients require an IOP check?

  • For first 3 visits to see if pressure rises.
  • All patients with glaucoma or OHT