Amoebiasis

Question 1

Named the Parasite as Amoeba Coli

Answer 1

Fedor Losch

Question 2

Renamed the parasite into Entamoeba Coli

Answer 2

Fritz Shaudinn

Question 3

Subphylum of Amoeba

Answer 3

Sarcodina

Question 4

Family of Amoeba

Answer 4

Entamoebidea

Question 5

Confined in the intestines but can be carried to other parts of the body

Answer 5

Amoeba

Question 6

Amoeba is aerobe or anaerobe?

Answer 6

Anaerobe

Question 7

Synonyms of Amoebiasis:

Answer 7

Amebiasis
Entamoebiasis 
Intestinal Amoebiasis
Amebic Dysentery
Walking Dysentery

Question 8

Causative agent of Amoebiasis:

Answer 8

Entamoeba histolytica

Question 9

2nd most common cause of diarrhea in travelers

Answer 9

Amoeba

Question 10

What kind is the Entamoeba histolytica?

Answer 10

Protozoa

Question 11

Drug used for Amoebiasis

Answer 11

Metronidazole

Question 12

Drug that causes aplastic anemia

Answer 12

Chloramphenicol

Question 13

Morphologically related to E. dispar and E. moshkovskii

Answer 13

Entamoeba histolytica

Question 14

2 forms of e. histolytica:

Answer 14

Hard, infective cysts

Fragile, pathogenic trophozoite

Question 15

Predominate in formed stools
Resist destruction in the external environment
Thick Chitin wall that contributes to resistance from acidic juices of stomach

Answer 15

E. histolytica cysts

Question 16

Feed on bacteria and tissue
Colonize lumen and mucosa of large intestine
Invade tissue and organs
Predominate in liquid stools

Answer 16

E. histolytica trophozoite

Question 17

3 Steps of Host Cell destruction:

Answer 17

1. Adherence
2. Cytolysis
3. Phagocytosis

Question 18

Initial contact of Amoeba is mediated by the parasite’s

Answer 18

N-acetyl D-galactosamine

Question 19

Final step in the apoptopic pathway:

Answer 19

Phagocytosis

Question 20

Limit inflammation by preventing spillage of toxic intracellular contents of dead cells

Answer 20

Phagocytosis

Question 21

Type of amoebiasis where cysts are absent in stools and trophozoites are fragile

Answer 21

Acute amoebiasis

Question 22

Type of amoebiasis that involves gastrointestinal symptoms plus fatigue, wt loss, and occasional fever

Answer 22

Chronic Amoebiasis

Question 23

Type of Amoebiasis; cysts in stool

Answer 23

Chronic Amoebiasis

Question 24

Any diarrheal episode in which the loose or watery stool contains visible red blood

Answer 24

Amoebic dysentery

Question 25

Occurs when the parasite invade the intestinal wall and abscesses may develop in the liver

Answer 25

Amoebic Dysentery

Question 26

Presents w/ fever and right upper quadrant abdominal pain

Answer 26

Liver abscesses

Question 27

Described the first proven case of Amoebic dysentery in St. Petersburg, Russia

Answer 27

Fedor Losch

Question 28

Participates in adhesion and cytotoxicity

Answer 28

Serine, Threonine, and Isoleucine Rich protein

Question 29

decreased virulence in animal model of amoebic liver

Answer 29

KERP

Question 30

Intestinal Diagnosis

Answer 30

Stool Examination PCR Serologic Test (IHA) Colonoscopy w/ Biopsy

Question 31

Liver diagnosis of Amoebiasis

Answer 31

Liver Aspiration Ultrasound Examination Serologic Test (ELISA)

Question 32

Incubation Period of Amoebiasis

Answer 32

2-4 weeks

Question 33

Visual inspection of the entire large bowel from the distal rectum to cecum

Answer 33

Sigmoidoscopy

Question 34

Use of crude extract of axenically cultured organism

Answer 34

Indirect Hemagglutination Assay

Question 35

Present in stool examination; due to breakdown of eiosinophils

Answer 35

Charcot Leyden Crystals

Question 36

Detects presence of anti-lectin antibodies IgG

Answer 36

Enzyme-Linked Immunoassay (ELISA)

Question 37

with WBC

Answer 37

Anchovy paste from liver

Question 38

without WBC

Answer 38

Anchovy paste from market

Question 39

Most common complication of Amoebiasis

Answer 39

Liver Abscesses

Question 40

Complication of Amoebiasis

Answer 40

Toxic Megacolon | Amoeboma

Question 41

Condition where the lining of the colon thickens due to flask-shaped ulcers

Answer 41

Amoeboma

Question 42

Virulence Factors of Amoeba

Answer 42

Gal/GalNac (Galactose and N-Acetyl-D-galactosamine) Cysteine Proteinases Amoebapore Myosin IV

Question 43

Virulence factor of Amoeba for binding

Answer 43

Gal/GalNac

Question 44

Virulence factor of Amoeba for Invasion; destruction of proteins

Answer 44

Cysteine Proteinases

Question 45

Virulence factor for the production of pores

Answer 45

Amoebapore

Question 46

Virulence factor of Amoebiasis for increased phagocytosos

Answer 46

Myosin IV

Question 47

Classification of Drugs for Amoebiasis

Answer 47

1. Luminal amoebicides | 2. Systemic Amoebicides

Question 48

Drugs that are active primarily against organisms in the colonic contents

Answer 48

Drugs active against organisms responsible for invasive diseases

Question 49

Loss of full control of body movements; adverse effect of Metronidazole

Answer 49

Ataxia

Question 50

Treatment of Amoebiasis in non-edemic areas; asymptomatic carriers; luminal amoebicide

Answer 50

Diloxanide

Question 51

Drug that is less toxic that Emetine; most effective but too irritant to be taken orally; alternative to metronidazole

Answer 51

Dehydroemetine

Question 52

Treatment of amoebic hepatic abscesses as an adjunct to dehydroemetine

Answer 52

Chloroquinone