Anal Ca

Question 1

Median age at diagnosis anal ca

Answer 1

61

Question 2

Hpv

Answer 2

Hpv 16 mc
-90% scc
Hiv-15-35 fold risk

Question 3

Homosexual risk

Answer 3

15 times higher risk

Question 4

Transplant with c/c immunosuppr rosk for anal ca

Answer 4

Six times

Question 5

Anal ca screening

In high risk only

Answer 5

Dre
Hra 
Colono
Anal pap and hpv
High risk- msm ,post transplnt , pho anal ca
, aids

Question 6

Treatment of high grade AIN

Answer 6

Ablation with electrocautery
• Topical trichloroacetic acid
• Topical 5-FU
Imiquimod

Question 7

Anal cytology sensitivity

Answer 7

80%

Question 8

What % of ain 3 to cancer

Answer 8

5%

Question 9

Pet ct changes nodal status in %?

Answer 9

21%

Tnm stage in 41%

Question 10

Tnm

Answer 10

T1- <2
2- 2-5
3->5
4-orgn involvement 
N1a-ing, mesorectal, int iliac
B- ext iliac
C- ext iliac+ any n1a

Question 11

Chemorad

Answer 11

Fu
Mitomycin
RT

Question 12

Correa scoring

Answer 12

Predicts postop apr survival rate
Factors- LN inv
Involved margins
Perineural or LVI
55% 5yr survival if no factors

Question 13

Metastatic anal ca
Chemo
Mc site

Answer 13

Mc site liver

Ct- carboplatin with paclitaxel

Question 14

Who clasfy ana adenoca into

Answer 14

Colorectal type
Anal gland
Fistula associated

Question 15

Adenocarcinoma arising in a fistula-in-ano has
been reported to have three characteristic
MRI findings:

Answer 15

Markedly hyperintense fluid on T2-weighted
images
b. Enhancing solid components
C. A fistula between the mass and the anus

Question 16

Treatment of adeno anal ca

Answer 16

Nacrt fb apr in more than 2 cm lesions