Thiracic Malignancies

Question 1

Smoker types

Answer 1

Never smoker less than 100 in lifetime
Ever more than hundred
Former stoped more than ayr back
Current stopped kes than yr or cureently smokin

Question 2

Lung cancer screening trials

Answer 2

NLST

Nelson

Question 3

Lungrads

Answer 3

0-4b
4a risk 5-15%
B- more than 15%
Solid more than 8 mm
Non solid more than 2 cm

Question 4

Mc histology

Answer 4

Adenocq

Question 5

Mets in lung ca at prese

Answer 5

50-70%

Question 6

Ihc for lung

Answer 6

Ttf1 and napsin a for adeno ca

Scc p40 and p63

Question 7

Anterior mediastinotomy aka

Answer 7

Chamberlain sx for sampling 5 and 6 ln stations

Question 8

Cervical mediastinoscopy nodes

Answer 8

2
4
7

Question 9

Stage 1 and 2 lung ca mgt

Answer 9

Anatomical surgical tt and mediastinal ln sampling

Question 10

Nodal sampling based on location

Answer 10

RIGHT UPPER AND MIDDLE LOBES: 7. 2R and 4R
RIGHT LOWER LOBE: 7, 4R, AND 8 OR 9
LEFT UPPER LOBE: 7.5 AND 6
LEFT LOWER LOBE: 7,8 AND 9.

Question 11

Ihc for mesothelioma

Answer 11

Wt1
Calretinin
Ck5/6
D2-40

Question 12

Sublobar lung resection criteria

Answer 12

Explanation
Segmentectomy (preferred) or wedge resection is appropriate in selected patients for the
following reasons:
Poor pulmonary reserve or other major comorbidity that contraindicates lobectomy
Peripheral nodule1 ≤2 cm with at least one of the following:
- Pure AIS histology
- Nodule has ≥50% ground-glass appearance on CT
- Radiologic surveillance confirms a long doubling time (>/= 400 days)

Question 13

Antibody drug conjugate

Answer 13

Rovalpituzumab tesirine

DLL3

Question 14

Adjuvant chemo above what level

Answer 14

1B

Question 15

Ct for lung ca

Answer 15

Non scc- Cisplatin pemetrexed

Scc- cisplatin gemcitabine or cis doce

Question 16

Small clell lung ca ihc

Answer 16

Ae1/3
Cam 5.2.1
Chromogranin 
Synaptophysin
Cd56
Ttf1
Insulinoma associated marker

Question 17

Sclc paraneoplasty

Answer 17

Extensive
Siadh 75%
Acth cushings 5%
Neurology lambert eaton syndrome

Question 18

Valsg staging limited disease

Answer 18

Tumor confined to hemithorax 
Ipsi pleural eff
Ipsi supraclav node
Ipsi and contra mediastinal node
But 2/3 patients present as extensive disease

Question 19

Sclc staging

Answer 19

Pet ct plus mri brain

Question 20

Stage 1-2A sclc

Answer 20

Surgery

Question 21

Sclc primary treatment

Answer 21

Chemo

Cisplatin and etoposide 4 cycles

Question 22

Limited stage disease treatment sclc

Answer 22

Concurent chemorad 4 cycles Efb prophykactic cranial irradiation 25 Gy
Memantine decreased neuro cohnitik decrease

Question 23

Extensive sclc treatment

Answer 23

Carboplatin etoposide
Atezolumab and maintain with atezolumab
Cisplatin etopo durvalumab

Question 24

Bronchal carcinoids second mc carcinoid site

Men?

Answer 24

Men1
75% central
68ga dotatate

Question 25

Typica or atypical carcinoid which mc

Answer 25

Typical 85%

Question 26

Carcinoid syndrome in lung carcinoids%

Answer 26

8%

Question 27

Mc cause of what hormone lung carcinoid

Answer 27

Extra pituitary ghrh

Question 28

Lcnec is

Answer 28

``` Mc adenoca Nsclc with ne features Mc symotom hemoptysis No ectopic hormones Worse survival Surgery same as nsclc Chemo same as sclc ```

Question 29

Popcorn appearance cxr

Answer 29

Hamartoma | Mc benign lung tumor

Question 30

Postop lung reserve fev1

Answer 30

Greater than 60% can tolerate anatomic lobectomy | V/P scan- ppo Fev1 35-40%

Question 31

Vo2 max cut off for lung resection

Answer 31

15ml kg min

Question 32

Tracheal ca mc

Answer 32

Scc -10% multifocal | > adenoid cystic ca

Question 33

Maximum resectable length of trachea

Answer 33

5 cm

Question 34

……% chest wall tumors are malignant

Answer 34

60%

Question 35

Mc benign tr of chest wall

Answer 35

Fibrous dysplasia

Question 36

Mc malignant bone tumor of chest wall

Answer 36

Chondrosarcoma

Question 37

Mc malignant promary chest wall tumr

Answer 37

Sts