Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Brain and Behavior II > Anesthesia Review > Flashcards

Anesthesia Review Flashcards

(97 cards)

Start Studying
1
Q

What class of drug is thiopental?

A

Barbiturate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

The electrical potential at which the sodium channel goes from the closed to the open state is also known as?

A

Threshold potential

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Do local anesthetics work at the internal or external membrane of the sodium channel?

A

Internal membrane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Thiopental is a strong base or strong acid?

A

Strong acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Which intravenous anesthetic also has a post-operative effect against nausea/vomiting (anti-emetic properties)?

A

propofol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

The unconsciousness induced by inhaled anesthetics is reversible or non-reversible?

A

Reversible

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Ketamine is most like what drug?

A

PCP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the treatment for local anesthetic toxicity?

A

Intralipid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

True or False: Local anesthetics do not block sympathetic nerve

A

FALSE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the effect of inhaled anesthetics on EEG?

A

“flatten it” isoelectric EEG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What disease is associated with inhaled anesthetics that increase the patient’s temperature and may result in death?

A

Malignant hyperthermia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Which inhaled anesthetic is least soluble in blood?

A

Desflurane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Which intravenous anesthetic resulted in more deaths at Pearl Harbor than the actual attack?

A

Thiopental

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Emergence from inhaled anesthetics depends on which: elimination or metabolism?

A

Elimination

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Which local anesthetic has more rapid onset: Bipivucaine (pKa= 8.1); Lidocaine (pKa=7.9)

A

Lidocaine (pKa is closer to that of body’s pH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Which induction agent is contraindicated in patients with egg allergy?

A

propofol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Which intravenous anesthetic has minimal effects on cardiovascular system?

A

Etomidate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

For which of the following drugs is the MOA clear: intravenous anesthetics, inhaled anesthetics, local anesthetics?

A

local anesthetics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Rapid induction of anesthesia is achieved with an inhaled or intravenous anesthetic?

A

Intravenous

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Maintenance of anesthesia occurs typically with an inhaled or intravenous anesthetic?

A

Inhaled

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What hair color increases MAC?

A

Red

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What is the effect of inhaled anesthetics on minute ventilation?

A

Goes down

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

For the inhaled anesthetics, speed of onset is determined by which property?

A

Blood solubility

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

What gas is typically administered for analgesia?

A

Nitrous oxide (used a lot in labor)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
What is the effect of inhaled agents on uterine tone?
decreases uterine tone
26
What does injection of intravenous opioids do to MAC?
decreases (i.e. when given opioids, you don't need as much anesthetic)
27
What do inhaled anesthetics do to the body's response to low blood oxygen?
Depresses this response
28
What do inhaled agents do to bronchomotor tone?
Relax it
29
What do inhaled agents do to cerebral blood flow?
Increases it (this is why increased cranial pressure is a contraindication)
30
The inhaled agents are supplied from the manufacturer in what form?
Liquid
31
What class of drugs are the inhaled anesthetics?
Ethers
32
For the termination of a drug's effect, which is more important: redistribution or elimination?
Redistribution
33
What drug is contraindicated in patients with acute intermittent porphyria?
Thiopental
34
What does propofol do to cerebral blood flow?
Decreases it
35
What is the amount of IV anesthetic to prevent awareness?
We don't know
36
Which IV anesthetic can also be given IM
ketamine (we use it for patients that have no IV access)
37
In addition to potassium chloride and pancuronium (sp?), which IV anesthetic is used for lethal injection?
Thiopental
38
Thiopental causes hypotension by myocardial depression and...?
Vasodilation
39
The term for the concept that the longer you infuse a drug, the longer it takes to eliminate?
Context-sensitive half-life
40
The term for how drugs get to the effect site
Pharmacokinetics
41
The term for drug effect as a result of receptor binding
Pharmacodynamics
42
What is the most common cause of death among anesthesiologists under 35
substance abuse
43
Give an example where EMLA ointment would be used?
lumbar puncture in pediatric patients
44
Which local anesthetic is also used as an anti-arryhthmic?
lidocaine
45
Which of the following OTC drugs contains a local anesthetic: hydrocortisone; Tylenol PM; Bactim; Milk of magnesia
Bactim
46
What agent is added to a local anesthetic to prolong the duration of blockade?
Epinephrine
47
When a certain area receives anesthetic and this area does not respond to natural stimuli, this is also known as?
Regional Anesthesia
48
What property of a local anesthetic influences its duration?
lipid solubility (also determines its potency)
49
What protein channel do local anesthetics work on?
Sodium channels
50
Which of the two stereoisomers of buvivicaine (sp?) is more cardiotoxic?
R enantiomer
51
What type of local anesthetic is cocaine?
Ester
52
Inhaled anesthetics have been linked to the progression of which disease in adults?
Alzheimer's Disease
53
The populational variance of inhaled anesthetics is large or small?
Small
54
Induction of anesthesia occurs at the beginning, middle, or end of anesthesia?
Beginning
55
The concentration of inhaled anesthetic necessary to prevent awareness is higher or lower than the amount needed to movement to pain?
Lower
56
Which inhaled anesthetic has the highest MAC?
Desflurane
57
Why is propofol used for sedation in the ICU?
it's quickly reversible
58
Which induction agent is also metabolized in the lungs and small intestine?
Propofol
59
Which local anesthetic was first used for surgery?
Cocaine
60
Which local anesthetic is more rapidly metabolized when injected intravenously?
Esters
61
Which organ metabolizes amide local anesthetics?
Liver
62
Is there an antagonist to the inhaled anesthetics?
No
63
Which depends on drug metabolism: distribution half-life or elimination half-life
Elimination half-life
64
Propofol potentiates the effects of which neurotransmitter?
GABA
65
The primary termination of clinical effectiveness in local anesthetics is what?
Redistribution half-life
66
Local anesthetics bind to which configurations of the sodium channel?
Open and inactive
67
The aromatic ring of the local anesthetic is hydrophilic or lipophilic?
Lipophilic
68
Which local anesthetic has greater potential for allergic reaction?
Ester (one I in generic name)
69
Which intravenous anesthetic does not depress respiration?
Ketamine
70
Which will achieve a peak level first: inhaled or intravenous anesthetics?
Intravenous
71
Inhaled anesthetics has been linked to the progression of which disease in kids?
Developmental delay (learning disability)
72
In the resting state, the sodium channel is in what configuration?
Closed
73
What is the first symptom of toxicity from lidocaine?
Numbness of tongue
74
Which local anesthetic causes vasoconstriction?
Cocaine
75
Inhaled anesthetics with a low blood solubility will have a slow or fast onset of action?
Fast
76
Which anesthetic agent would be best for someone scheduled to go home?
Propofol
77
When the entire body does not respond to noxious stimuli, that's also known as?
General Anesthesia
78
What is the breakdown product of ester local anesthetics?
Para-benzoic acid (PABA)
79
Which IV anesthetic increases intracranial pressure?
Ketamine
80
Which organ is the primary site of metabolism for IV anesthetics?
liver
81
Do inhaled agents provide analgesia?
Yes
82
What do local anesthetics bind in the blood?
Albumin and alpha-1 glycoprotein
83
What is the effect of inhaled anesthetics on blood pressure?
Decreases it
84
Which IV anesthetic increases ICP and cerebral blood flow?
Ketamine
85
Local anesthetics are weak acids or weak bases?
Weak bases
86
The pKa of a local anesthetic determines what of the anesthetic?
The speed of onset
87
Name the two intermediate chains of local anesthetics
esters and amides
88
What is the term for the concentration of vapor that prevents movement and response to surgical incision in 50% of population?
MAC: minimum alveolar concentration
89
Which term describes an unaware patient who does not respond to pain?
anasthesia
90
Which of the following organs has the greatest uptake of local anesthetic following accidental IV injection: stomach, brain, muscle, skin?
brain
91
Which IV anesthetic has analgesic properties?
Ketamine
92
What determines speed of onset of inhaled anesthetics, assuming same concentration and minute respiration?
Blood solubility
93
What is the effect of inhaled anasthetics on temperature?
Decreases it
94
What property of a local anesthetic influences its potency?
Lipid solubility
95
Which IV anasthetic causes adrenocortical suppression?
Etomidate
96
What enzyme hydrolyzes ester local anasthetics?
pseudocholinesterase
97
True/False: Anti-histamines have sedative hypnotic effect?
TRUE

Brain and Behavior II (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions