Animal Bite II

Question 1

Bartonella henselae General

Answer 1

Small, aerobic pleomorphic, short gram – rod, facultative intracellular

Question 2

Bartonella henselae Animal Bite

Answer 2

Saliva of cats

Question 3

Bartonella henselae Clinical

Answer 3

CAT SCRATCH DISEASE: regional lymphadenitis after a papule at a cat scratch site, UNILATERAL REGIONAL LYMPHADENITIS (#1 cause), benign and self limiting disease

Question 4

Bartonella henselae Lab findings

Answer 4

Difficult to culture and gram stain

WARTHIN-STARRY SILVER STAIN

Question 5

Bartonella henselae Dx/ Treatment

Answer 5

Dx based on history and physical findings, negative studies for other causes, histopathology of lymph node biopsy, no Culture

Question 6

Bartonella Bacilliformis? General

Answer 6

Small, aerobic pleomorphic, short gram

Question 7

Bartonella Bacilliformis? Animal Bite

Answer 7

Sand fly

Question 8

Bartonella Bacilliformis? Clinical

Answer 8

Oroya Fever: acute febrile infection with severe anemia in Peru, Ecuador, Columbia

Question 9

Bartonella Quintana General

Answer 9

Small, aerobic pleomorphic, short gram

Question 10

Bartonella Quintana Clinical

Answer 10

Trench Fever: severe HA, fever, bone pain, endocarditis and bacilliary angiomatosis in immune compromised

Question 11

Bartonella Clarridgeiae? General

Answer 11

Small, aerobic pleomorphic, short gram

Question 12

Bartonella Clarridgeiae? Clinical

Answer 12

Endocarditis, cat scratch disease

Question 13

Bartonella Elizabethae? General

Answer 13

Small, aerobic pleomorphic, short gram

Question 14

Bartonella Elizabethae? Clinical

Answer 14

Endocarditis

Question 15

Streptobacillus moniliformis General

Answer 15

Aerobic, gram neg bacillus, pleomorphic (bead string), fastidious

Question 16

Streptobacillus moniliformis Animal Bite

Answer 16

Oropharynx of rodents (rats)

Question 17

Streptobacillus moniliformis Clinical

Answer 17

Minimal local inflammation, prompt healing, little lymphadenitis
Rat Bite fever: septic fever, petechial rash, polyarthritis, HA, N/V, anemia, pneumonia
Often confused with RMSF

Question 18

Streptobacillus moniliformis Dx

Answer 18

Slow growth can be cultured in vitro

Dx: culture of blood

Question 19

Spirillum Minor General

Answer 19

Gram neg bacillus

Small, spiral shape, DARTING MOTILITY

Question 20

Spirillum Minor Animal Bite

Answer 20

Oropharynx of rodents

Question 21

Spirillum Minor Clinical

Answer 21

Long incubation period, recurrent fever, less prominent rash, common in Asia
Rat bite fever
Lymphagitis, Lymphadenopathy

Question 22

Spirillum Minor Treatment/Dx

Answer 22

Dx: dark field prep of blood smears or tissue or from pus or adjacent lymph nodes
-Giemsa’s or Wrights stain

Question 23

Rhabdovirus (Rabies) General

Answer 23

ssRNA virus

Bullet shaped

Question 24

Rhabdovirus (Rabies) Animal Bites

Answer 24

Zoonotic, racoons, skunks, BATS, dogs, cats, cattle etc.

Question 25

Rhabdovirus (Rabies) Clinical

Answer 25

Infection of skeletal muscle then travel to CNS
Furious rabies: aggressive behavior, agitation, confusion, excessive salvation, hydrophobia
Dumb rabies: weakness, inability to swallow/choke

Question 26

Rhabdovirus (Rabies) Dx/Treatment

Answer 26

Post mortem: antigen detection in brain, presence of Negri bodies
Prophylaxis and post exposure therapy