Ankylosing spondylitis Flashcards
1
Q
seronegative spondyloarthropathies
A
AS
psoriatic arthritis
enteropathic arthritis
reactive arthritis
2
Q
gene association
A
HLA B27
3
Q
which joints affected?
A
sacroiliac
axial spine
4
Q
hallmark clinical feature
A
inflammatory back pain
5
Q
inflammatory back pain
A
insidious onset
worse in morning
improves with exercise
6
Q
do most patients respond to NSAIDs?
A
yes
7
Q
3 main treatment approaches
A
physiotherapy
NSAIDs
TNF alpha inhibitors
8
Q
x-ray - spinal fusion
A
bamboo spine
9
Q
key diagnostic factors
A
risk factors
inflammatory back pain
iritis/uveitis
enthesitis
10
Q
risk factors
A
HLA-B27
family history
klebsiella pneumoniae
11
Q
1st investigation
A
pelvic x-ray
12
Q
investigations to consider
A
HLA-B27
MRI
cervical/lumbar x-ray
CRP, ESR
13
Q
key complication
A
vertebral fractures
14
Q
associated symptoms
A
weight loss, fatigue chest pain dactylitis anaemia restrictive lung disease IBD
15
Q
What test is done (OSCE)
A
Schobers
