Lymphoma Flashcards
(29 cards)
where do the cancerous cells proliferate?
LN
2 main types
hodgkins
non-hodgkins
hodgkins lymphoma epidemiology
1 in 5 lymphomas
proliferation of lymphocytes
bimodal age -20 and 75
risk factors hodgkins lymphoma
HIV
EBV
autoimmune disorder
FH
presentation of hodgkins lymphoma
lymphadenopathy - neck, axilla, inguinal region
LN hodgkins lymphoma
non-tender
rubbery
when might those with hodgkins lymphoma feel pain in LN?
alcohol
B symptoms
night sweats
weight loss
fever
other hodgkins lymphoma symptoms
fatigue itching cough SOB abdominal pain recurrent infections
hodgkins lymphoma investigations
bloods - FBC, LDH
LN biopsy
hodgkins key diagnostic test
LN biopsy
key finding biopsy - hodgkins
reed-sternberg cell
reed-sternberg cell
abnormally large B cells
multiple nuclei - nucleoli inside (face of owl with large eyes)
staging system
ann arbor
what does ann arbor staging put importance on?
nodes above or below diaphragm
ann arbor staging - how many?
4
ann arbor stages
1 = 1 region of LN 2 = more than 1 region on same side of diaphragm 3 = LN above and below diaphragm 4 = widespread - liver, lungs
key treatments hodgkins
chemo and radiotherapy
what does chemo create a risk of?
leukaemia
infertility
what does radiotherapy create a risk of?
cancer
hypothyroidism
damage to tissues
3 noteable types of NHL
burkitt lymphoma
MALT
diffuse large b cell
burkitt lyphoma associations
HIV, EBV, malaria
MALT lymphoma
MALT around stomach
h pylori
risk factors for NHL
HIV, EBV, h pylori
hep B or C
pesticides - trichloroethylene
FH
