ANS Drugs

Question 1

Phenylephrine (Neo-synephrine)

Answer 1

Alpha 1 adrenergic agonist

-Nasal congestion, hypotension, pupil dilation

Question 2

Clonidine (Catapress)

Answer 2

Alpha 2 adrenergic agonist

-HTN, severe pain, BP

Question 3

Methyldopa (Aldomet)

Answer 3

Alpha 2 adrenergic agonist

–HTN, severe pain, BP

Question 4

Albuterol

Answer 4

Selective for beta 2 adrenergic agonist *

• Asthma, reduce preterm labor contractions
• Hyperglycemia in diabetics, tremors

Question 5

Isoproterenol

Answer 5

Nonselective beta adrenergic agonist

Question 6

Dobutamine

Answer 6

Beta adrenergic agonist

-Heart attack, failure, shock, AV heart block, cardiac arrest, profound hypotension

Question 7

Epinephrine (Adrenalin)

Answer 7

Nonselective adrenergic agonists*

• Shock, V-fib, simple glaucoma/cataracts, GI hemorrhage, hyperkalemia, wheezing in infants, hypotension, cardiopulmonary resucitation
• Active labor, closed angle glaucoma, sulfite sensitivity, dysrhythmias, CAD, labor, HTN, hyperthyroidism

Question 8

Ephedrine

Answer 8

Nonselective adrenergic agonists

Question 9

Norepinephrine (Levophed)

Answer 9

Nonselective adrenergic agonists

Question 10

Vasopressin

Answer 10

Nonselective adrenergic agonists

Question 11

Prazosin (Minipress)

Answer 11

Alpha 1 adrenergic antagonists

-HTN, CHF, Raynaud’s, prostatic outflow obstruction by competing with NE

Question 12

Tamsulosin (Flomax)

Answer 12

Alpha 1 adrenergic antagonists

-Reduce the contraction of smooth muscle in prostate and bladder neck

Question 13

Doxazosin (Cardura)

Answer 13

Alpha adrenergic antagonists

Question 14

Propranolol, metroprolol, atenolol

Answer 14

Beta adrenergic antagonists

-Cardiac, glaucoma, anxiousness, migraines

Question 15

Atropine

Answer 15

Antidote for parasympathetic nervous system

Question 16

Pilocarpine

Answer 16

Direct-acting muscarinic agonists

-Open angle glaucoma, angle-closure glaucoma, induction of miosis (decrease pressure)

Question 17

Acetylcholine

Answer 17

Direct-acting muscarinic agonists

Question 18

Bethanecol

Answer 18

Direct-acting muscarinic agonists

Question 19

Nicotine

Answer 19

Direct-acting nicotinic agonists

Question 20

Neostigmine (Prostigmin)

Answer 20

Indirect-acting cholinergic agonists*(cholinesterase inhibitor) Ach ^

• skeletal muscle contractions, reverse neuromuscular blocking agents, glaucoma, prophylaxis of nerve gas poisoning
• GI obstruction/ileus, GU obsturction, peptic ulcers, cardiac patients, resp patients

Question 21

Physostigmine/Pryidostigmine

Answer 21

Indirect-acting cholinergic agonists(cholinesterase inhibitors) Ach ^

-Myasthenia gravis

Question 22

Atropine

Answer 22

Cholinergic antagonists

-Bradycardia, pulselessness electrical activity, asystole, CPR, decrease resp secretions, block cardiovagal reflexes, arrthymias, duodenal ulcers, IBS, cycloplegia (paralysis of cilliary muscles), iritis

Question 23

Benztropine

Answer 23

Cholinergic antagonists

Question 24

Scopolamine

Answer 24

Cholinergic antagonists

-Motion sickness, drying secretions, N/V