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Flashcards in ANS: Stress Response Deck (19)
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1

What are the components of the CNS?

1. Brain
2. Spinal cord

2

What do afferent nerves do?

Sensory neurons, deliver info from external environment to brain

3

What do efferent nerves do?

Motor neurons, deliver info from brain to peripheral structures

4

What does the ANS do?

Part of peripheral nervous system, regulates involuntary functions

5

What comprises the PSNS?

Arises from brain stem via CNS.
CN X Vagus controls 75% of PSNS functions. Also includes spinal and sacral nerves

6

What comprises the SNS?

Arises from the spinal cord via thoracic and lumbar areas.
Includes SNS specific neurotransmitters (catecholamines)

7

What are catecholamines?

Neurotransmitters associated with SNS
1. Norepinephrine
2. Epinephrine
3. Dopamine

8

What are sympathomimetics?

Synthetic drugs that mimic cathecholamines to activate alpha, beta, dopaminergic receptors of SNS

9

How does neurotransmission work?

1. Impulse travels to presynaptic membrane
2. Presynaptic membrane releases NTs into the synapse
3. NTs fit onto specific receptor sites
4. Enough NTs attaching = organ effect

10

What NTs alpha adrenoceptors receptive to?

What types of alpha receptors are there and what do they effect?

Receptive to norepinephrine, epinephrine, dopamine

Alpha 1 receptors effect vascular smooth muscle. Vasoconstriction. Found in systemic vessels, heart, GI tract

Alpha 2 receptors provide negative feedback loop that usually inhibits release of catecholamines

11

What do alpha 2 agonists do?

Targets alpha 2 receptors, activates negative feedback loop, suppresses SNS, calms pt from anxiety, can decrease BP

12

What NTs are beta adrenoceptors receptive to?

What types of beta receptors are there and what do they do?

Receptive to epinephrine (B1), norepinephrine, dopamine

Beta 1 receptors effect the heart
1. Cronotropic (HR)
2. Inotropic (Contractility)
3. Dromotropic (Conduction)

Beta 2 receptors effect the lungs and will cause bronchodilation (smooth muscle relaxation)

13

What NTs are dopaminergic receptors receptive to? What does it do?

Receptive to dopamine. Effects blood vessels to kidney, kidney itself, causes slight diuresis via vasodilation

14

What NTs are present in the PSNS?

Acetylcholine attaches to cholinergic receptors to activate PSNS

15

What would an anti-cholinergic med do?

Suppresses effects of overactive PSNS (Glycopyrralate reduces secretions, drooling)

16

What does epinephrine primarily effect?

Primarily effects Beta 1 receptors and will increase HR, FOC, conduction. Give in cases of bradycardia, not so much with volume issues.

17

What med do you give to vasoconstrict the pt?

Levo, vasopression

18

What med do you give to increase cardiac function or bronchodilate?

Epi

19

How does dopamine dosage effect function?

Low dose --> dopaminergic (renal dose), kidney vasodilation and diuresis
Med dose --> Beta / dopinergic effects. Increase cardiac function
High dose --> Alpha / beta effects. Vasoconstriction