Antenatal and Perinatal Pharm Flashcards

1
Q

misoprostol

A
  • induction of labor
  • synthetic PGE1 analog
  • causes uterine contractions
  • keep ductus arteriosus patent
  • can also be used for termination, or for cervical ripening
  • risk of n/v, chills and shivering, abnormal uterine contraction
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2
Q

dinoprostone

A
  • induction of labor
  • synthetic PGE2 analog
  • induces uterine contractions and promotes cervical ripening
  • given as a cervical insert, or vaginal gel
  • can cause fever that is unresponsive to NSAIDS
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3
Q

carboprost

A
  • induction of labor
  • synthetic F2α analog
  • causes uterine contractions
  • can be used for termination, and post-partum hemostasis
  • risk of pulmonary edema d/t vasoconstriction, fevers and chills, choking sensation and gagging
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4
Q

oxytocin

A
  • induction of labor
  • increases force, frequency and duration of uterine contractions
  • also used for post-partum hemostasis
  • do not use if fetal lungs are undeveloped, or if cervix is not softened
  • risk of hyponatremia
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5
Q

ergot alkaloids

A
  • induction of labor
  • stimulates adrenergic, dopaminergic, and serotonergic receptors to cause extended uterine contractions
  • given for post-partum hemostasis
  • risk of st. anthony’s fire
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6
Q

alprostadil

A
  • maintains patent ductus arteriosus

- synthetic PGE1

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7
Q

indomethacin

A
  • closes ductus arteriosus
  • tocolytic
  • risk of gerd, gastritis, and emesis
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8
Q

ibuprofen

A

-closes ductus arteriosus

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9
Q

cortisol
betmethasone
dexamethasone

-Which is Fluorinated?

A

-corticosteroid

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10
Q

erythromycin ointment

A

-antibiotic used to prevent gonococcal eye infections in newborns

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11
Q

vitamin k

A

-prevents bleeding

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12
Q

hepatitis B vaccine give when>

A

-given w/in 24 hr

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13
Q

terbutaline

A
  • β2 agonist that acts as a tocolytic
  • increases cAMP and leads to K+ channel mediated hyperpolarization
  • risk of hypotension, SOB, tachycardia, arrhythmias
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14
Q

nifedipine

A
  • CCB that acts as a tocolytic

- risk of hypotension, flushing, palpitations

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15
Q

MgSO4

A

-tocolytic

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16
Q

atosiban

A
  • tocolytic
  • blocks action of oxytocin
  • not available in US
17
Q

α-methyldopa
Labelatol
Hydralzaine
Sodium Nitroprusside

Which is First line?

A

-antihypertensive

α-methyldopa
Labelatol