Anti-Migranes, -Parkinsoninan Drugs Flashcards
(18 cards)
Acute migraine attack meds are: (2 categories)
- NSAIDS ( otc= tylenol ; Rx= indocin toradol,
Voltaren)
-Triptans ( imatrex or product Trexima) -
vasoconstriction
Drug class for imatrex
i. 5-HT1B/1D receptor agonists
______ = progressive degeneration of dopamine secreting neurons in the _______?
Parkinsons ; substantia nigra
Tx for Parkisons (5 drugs)
- Sinemet ( Levadopa/carbedopa)
-Elderpyrl ( MOAB)
(elderly drinks MAOB, if drinks epi = HTN) - Mirapex (DA agonist)
-Entacapone – COMT blocker
“Al CAPONE COck BLKs with Abx”
-Benztropine (Cogentin)
“Parkinson men wak like carrying BEEMS”
____ combines sumatriptan and naproxen
Trixema
Preventative migraine meds
-BP meds ( BB, CCB)
-Anticonvulsants -
valproic acid, Topimax TCAs (Amitriptyline)
_____ caused compulsive gambling in some patients
Mirapex
Sx options for parkinson
Deep Brain Stimulation
Gene therapy
Dental concerns in treating the Parkinson’s patient (3)
- oral tremors
- Xerostomia
- DDI with epi containing local & elderpyrl
Pt taking erythromycin and ampicillin wtih _____ = biliary excretion will be reduced
entacapone
limit epi to 3 cartridges to avoid hypertensive crisis potential with which drug
Levadopa
Selegilene is an MAOI – avoid ???
meperidine
______ increase BP and sensitize myocardium to arrhythmias, thus caution with epi ( also hepatox with erythro)
COMT BLKRS (entacapone)
Deficits in activity of which NT in Parkinson’s? NE DA SR ACH
DA
Sinemet treats? Migranes Parkinson Epilepsy Bipolar Neuropathic pain
PARKINSON
Med to tx _____ may interact adversely with epi
Parkinsons
migranes
seizures
PARKINSON
Anticonvul, BB, triptans = tx migranes. Which are abortive?
Anticonvul
BB
Triptans
TRIPTANS
Eldepryl acts as a \_\_\_\_and tx \_\_\_? 5HT agonist, Parkinson Na Channel inactivate, epilepsy MAO-B, Parkinson GABBA, migraines DA agonist – neuropathic pain
MAOB ; PARKINSON
