Antibiotic Administration! Flashcards Preview

Pharmacy Pre-Registration 20/21 > Antibiotic Administration! > Flashcards

Flashcards in Antibiotic Administration! Deck (11)
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1
Q

Which antibiotics should be taken WITH OR JUST AFTER FOOD

(extra warning label)??

A

Metronidazole

Nitrofurantoin

Clarithromycin MR

2
Q

Which antibiotics should be taken ON AN EMPTY STOMACH i.e. 2 hours before or 2 hours after food

(extra warning label)

A

Penicillin (Penicillin V- Phenoxymethylpenicillin)

Ampicillin

Flucloxacillin

Rifampicin

3
Q

Which antibiotics should MILK be avoided 2 hours before or 2 hours after taking, as MILK DECREASES THEIR ABSORPTION?

A

Ciprofloxacin

Tetracyclines:

Oxytetracycline

Tetracycline

Demeclocycline

As MILK contains CALCIUM- chelate to this forming a complex that cannot be absorbed

4
Q

Which antibiotics SHOULD BE TAKEN WITH A FULL GLASS OF WATER (extra warning label)?

A

Certain Tetracyclines:

Doxycycline

Minocycline

Tetracycline

also

CLINDAMYCIN

METRONIDAZOLE

To avoid irritation of the oesophagus

5
Q

Antacids contain calcium, magnesium and aluminium metal ions. Medicines containing IRON/ ZINC can also affect absorption. What antibiotics need to be taken 1 hour before or 2 hours after antacids/ iron or zinc products, and why?

NB: There is a cautionary label that incorporates both antacids and iron/zinc products: this is needed

A

Antibiotics can chelate with the metal ions and this will reduce the antibiotics absorption:

Tetracycline, oxytetracycline, doxycycline- remember these are contra-indicated in children under 12 years due to deposition in bones/ teeth (calcium binding- also avoided with milk)

Quinolones: Ciprofloxacin, levofloxacin, moxifloxacin

Nitrofurantoin- Magnesium only

6
Q

What are the counselling points/ extra warning labels with Metronidazole?

A

Take WITH or just after FOOD

WITH A FULL GLASS OF WATER

Do NOT drink ALCOHOL

7
Q

What are the counselling points/ extra warning labels with DOXYCYCLINE?

A

Do not take indigestion remedies (antacids)/ med’s containing iron or zinc 2 hours before/ after

Drink with a full glass of water

Protect skin from sunlight- even on cloudy day

Space evenly throughout day

8
Q

What extra warning label do

Ciprofloxacin

Oxytetracycline

Tetracycline

Demeclocycline

All share?

A

Do not take milk, indigestion remedies or med’s contaning iron/ zinc 2 hours before or after

9
Q

What are the extra warning labels for Isoniazid (used in TB)?

A

Take 30 to 60 mins before food

Do not stop taking unless doctor says (as its for TB- needed for long time!)

10
Q

What are the extra warning labels for azithromycin?

A

DO not take indigestion remedies/ antacids at same time

Space doses evenly

NB: here the mention of zinc/iron products not needed

11
Q

What are the extra warning labels for Nitrofurantoin?

A

May colour the urine (yellow/ brown)

Take with or just after food

Space doses evenly, don’t stop taking unless told to

Decks in Pharmacy Pre-Registration 20/21 Class (82):