Treating Toxicity COPY Flashcards Preview

Pharmacy Pre-Registration 20/21 > Treating Toxicity COPY > Flashcards

Flashcards in Treating Toxicity COPY Deck (20)
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1
Q

How do you treat convulsions caused by overdose/poisoning?

A

If over 5 minutes in duration must give IV Diazepam or Lorazepam. If IV not available give buccal midazolam or rectal diazepam.

2
Q

How can you treat toxicity from carbamazepine, phenobarbital, quinine, theophylline or dapsone?

A

Repeated doses of charcoal

3
Q

Symptoms of aspirin poisoning?

A

Hyperventilating, tinnitus, deafness, sweating.

4
Q

How do you treat aspirin poisoning?

A

Treat using charcoal and sodium bicarbonate to increase the urinary excretion (make sure to correct the K+ concentration before)

5
Q

Symptoms of paracetamol poisoning?

A

Nausea and vomiting

6
Q

How do you treat paracetamol poisoning?

A

Acetylcysteine-most effective when given 8 hours after ingestion

7
Q

How do you treat antidepressant poisoning? e.g Tricylic antidepressants, SSRIs

A

Activated charcoal to limit absorption and sodium bicarbonate to increase urinary excretion and stop arrhythmias

8
Q

What TWO drugs can you use to treat dystonia from an overdose on phenothiazines ie chlorpromazine or prochlorpromazine?

A

Procyclidine or diazepam

9
Q

What is used to treat benzodiazepine overdose?

A

Flumazenil

10
Q

What is used to treat a betablocker overdose?

A

Atropine IV (reverses bradycardia)

11
Q

What is used to treat calcium channel blocker overdose? (HINT-4)

A

Charcoal, calcium chloride, calcium gluconate, atropine (for bradycardia)

12
Q

What are the signs of lithium toxicity?

A

> 2mmol/L plasma concentration and symptoms including vomiting, ataxia, tremor, convulsions, coma

13
Q

How do you treat lithium toxicity?

A

Haemodialysis ie increase fluid intake to increase urine output

14
Q

How do you treat a cocaine or MDMA overdose?

A

IV diazepam to reduce agitation and cooling measures to reduce hyperthermia

15
Q

How do you treat iron poisoning?

A

Desferrioxamine mesilate (deferoxamine)

16
Q

Signs of theophylline toxicity?

A

Agitation, tachycardia, hyperglycemia, hypokalaemia

17
Q

How do you treat theophylline toxicity?

A

Repeated doses of activated charcoal, manage hypokalaemia with IV KCL, short acting beta blocker e.g esmolol for severe tachycardia

18
Q

Signs of digoxin toxicity?

A

Nausea and vomiting, yellow vision, irregular heart beat, confusion

19
Q

How do you treat digoxin toxicity?

A

Antidote is digifab (a digoxin specific antibody)

20
Q

How do you treat heparin toxicity?

A

Protamine sulphate IV

Decks in Pharmacy Pre-Registration 20/21 Class (82):