Antibiotic mechanisms Flashcards
(6 cards)
0
Q
Ceftriaxone mechanism. Cross BBB?
A
Binds to penicillin binding protein to inhibit cell wall synth
Yes crosses BBB
1
Q
Amoxicillin/Ampicillin mechanism
A
Cell wall inhibitor bind to PBP
2
Q
Aztreonam mechanism
A
PBP inhibiting, can’t be broken by beta lactamases
3
Q
Vancomycin mechanism
A
Cell wall inhibitor binds to D-ala-D-ala shielding it from transpeptidation reaction
4
Q
Rifampin mechanism
A
Inhibits DNA dependent RNA polymerase, increasing P450 levels decreasing activity of other drugs
5
Q
Gentamicin and amikacin mechanism
A
Protein synthesis inhbitor, bind to 30S subunit
