Antifungals Flashcards by Jay Allen

Q

Nephrotoxic drug

A

Amphotericin B

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Q

Amphotericin B mechanism

A

Binds ergosterol causing leakage of electrolytes through the plasma membranes

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Q

Used for visceral leishmaniasis as well

A

Amphotericin B

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Q

Flucytosine mechanism

A

DNA synthesis inhibitor conversion to 5 FU

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Q

Treat cryptococcus, candida infections

A

Flucytosine and amphotericin B

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Q

Candida treatment

A

Fluconazole

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Q

Fluconazole mechanism

A

Decrease ergosterol synthesis

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