Antibiotic therapy 1 Flashcards

1
Q

bacteriostatic

A

inhibit growth of bacteria

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2
Q

bacteriocidal

A

kill bacteria

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3
Q

narrow spectrum

A

against gram positive

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4
Q

broad spectrum

A

against many gram positives and negatives

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5
Q

has the ideal antibiotic got a long or short half life

A

long

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6
Q

beta lactam antibiotics

A

penicillins and cephalosporins

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7
Q

example of cephalosporins

A

Ceftriaxone

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8
Q

example of glycopeptides

A

vancomycin

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9
Q

cell wall targeting antibocs

A

penicillins
glycopeptides
cephalosporins

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10
Q

target of beta lactams

A

penicillin binding proteins

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11
Q

d-alanine d-alanine

A

component of bacterial peptidoglycan

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12
Q

what do beta lactams resemble

A

D-alanine D-alanine dipeptide & irreversibly binds PBP

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13
Q

penicillin assoc

A

ecreted rapidly
safe in pregnancy
safe

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14
Q

limitations of penicillins

A

allergic
rapid excretion so frequent dosing
resistance

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15
Q

beta lactamases

A

enzymes which destroy beta lactam ring

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16
Q

co amoxiclav

A

beta lactam and beta lactamase inhibitor

17
Q

is flucoxacillin narrow or broad spec

A

narrow

18
Q

what is resistant to flucox

A

MRSA

19
Q

what is flucox commonly prescirbed for

A

staph and strep skin infections

20
Q

beta lactamase resistant form of penicilin

A

temocillin

21
Q

which penicllin for gram positive organisms

A

flucox

22
Q

which penicillin for gram pos and neg

A

amoxicillin, co amox, piperacillin/ tazobactam

23
Q

which penicillin for gram neg

A

temocillin

24
Q

are penicillins bacteriostatic or cidal

A

cidal

25
Q

are cephalosporins static or cidal

A

cidal

26
Q

are cephalosporins broad or narrow

A

broad

27
Q

what antibocs causes c.diff

A

cephalosporins

28
Q

are glycopeptides cidal or static

A

cidal

29
Q
A