Antibiotic therapy 1 Flashcards
bacteriostatic
inhibit growth of bacteria
bacteriocidal
kill bacteria
narrow spectrum
against gram positive
broad spectrum
against many gram positives and negatives
has the ideal antibiotic got a long or short half life
long
beta lactam antibiotics
penicillins and cephalosporins
example of cephalosporins
Ceftriaxone
example of glycopeptides
vancomycin
cell wall targeting antibocs
penicillins
glycopeptides
cephalosporins
target of beta lactams
penicillin binding proteins
d-alanine d-alanine
component of bacterial peptidoglycan
what do beta lactams resemble
D-alanine D-alanine dipeptide & irreversibly binds PBP
penicillin assoc
ecreted rapidly
safe in pregnancy
safe
limitations of penicillins
allergic
rapid excretion so frequent dosing
resistance
beta lactamases
enzymes which destroy beta lactam ring