important

Question 1

flouroquinolones assoc

Answer 1

mainly active against gram negative
may cause tendonitis
not for pregnancy
disrupts cartilage in growing kids
new like levoflox is active agaisnt gram psitive
can prolong qt interval
ciprofloxacin is active against pseudomonas
DNA inhibitor

Question 2

aminoglycosides assoc

Answer 2

active against gram negatives
can act with penicillin to get throughgram wall
active against klebsiella, tb, pseudomonas and e.coli
side effects include nephrotoxicity, ototoxicity
act on 30s ribosome

Question 3

tetracyclines assoc

Answer 3

bind to a site on 30s ribsoosme
broad spec
phototoxicity- more likely to get sunburnt
accumulate in teeth and bones
contra in preg
nephrotoxic

Question 4

dna syntheiss inhibitors

Answer 4

metronidazole, trimethoprim, flouroquinolones

Question 5

protein inhibtors

Answer 5

macrolides, aminoglycosides, tetracylines